Evidence map›Paper›PMID 36672084›Full record

ArticleBrain sciences2023

Acute Visual Impairment in a Patient with Parkinson's Disease after Successful Bilateral Subthalamic Nucleus Deep Brain Stimulation with Low-Dose Levodopa: A Case Report.

Chao Zhang, Jinxing Sun, Zhenke Li, Na Liu, Chao Li

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chao ZhangDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250100, China.ORCID 0000-0001-5930-3602
Jinxing SunDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250100, China.
Zhenke LiDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250100, China.
Na LiuDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250100, China.
Chao LiDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250100, China.
Shandong University · CNQilu Hospital of Shandong University · CN

Funding

National Natural Science Foundation of China 81702469Natural Science Foundation of Shandong Provience ZR2022MH155
6 · The paper itself

Abstract

backgroundSubthalamic nucleus deep brain stimulation (STN-DBS) is widely used for the treatment of primary motor symptoms in patients with Parkinson's disease (PD). Further, recent evidence suggests that STN-DBS may relieve a few ophthalmic symptoms in PD, such as eye-blink rate and the flexibility of eye saccades. However, its exact effect on visual function remains unknown. Herein, we report the case of a patient with PD who underwent STN-DBS and experienced visual symptoms following levodopa reduction. CASE PRESENTATION: A 63-year-old male patient with PD developed severe visual impairment after six months of high-frequency STN-DBS. His symptoms resolved after adjusting the levodopa dose prescribed to the patient.

conclusionsThis case report suggests that DBS is beneficial in patients with PD in terms of eye-blink rate. However, the rapid reduction of medication after STN-DBS may lead to retinal atrophy and the shrinkage of vessel density in the ocular fundus. Thus, neurosurgeons should pay close attention to patients with visual symptoms when adjusting levodopa dosages.

Indexed as

deep brain stimulationParkinson’s diseasesubthalamic nucleusvisual symptoms

Identifiers

PMID36672084
PMCPMC9857186
OpenAlexW4313570465

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.