ArticleBrain sciences2023
TED-Trazodone Efficacy in Depression: A Naturalistic Study on the Efficacy of Trazodone in an Extended-Release Formulation Compared to SSRIs in Patients with a Depressive Episode-Preliminary Report.
Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The effects of trazodone exposure during pregnancy on fetal outcomes: a systematic review.European journal of clinical pharmacology · 2025Pooled it
- Trazodone effectiveness in depression (TED): a comparative evaluation of effect sizes trazodone extended release and SSRIs in the treatment of major depressive disorder.Frontiers in pharmacology · 2026Article
- The value of observational studies in MDD research based on the example of trazodone once-a-day.Neuroscience applied · 2026Article
- PtNiSnOInternational journal of molecular sciences · 2025Article
- Targeting heterogeneous depression with trazodone prolonged release: from neuropharmacology to clinical application.Annals of general psychiatry · 2025Article
- Insulin Resistance, Temperament and Personality Traits Are Associated with Anhedonia in a Transdiagnostic Sample.Brain sciences · 2024Article
- Trazodone effectiveness in depression: impacts of trazodone extended release vs SSRIs on the health status and quality of life of patients with major depressive disorder.Frontiers in pharmacology · 2024Article
- Case report: Personalizing the use of trazodone in real-world patients: a study of three cases of depression with comorbidities.Frontiers in psychiatry · 2024Article
- Neuroimaging Study of Brain Functional Differences in Generalized Anxiety Disorder and Depressive Disorder.Brain sciences · 2023Article
- Role of trazodone in treatment of major depressive disorder: an update.Annals of general psychiatry · 2023Review
- Trazodone in the Management of Major Depression Among Elderly Patients with Dementia: A Narrative Review and Clinical Insights.Neuropsychiatric disease and treatment · 2023Article
- TED-trazodone effectiveness in depression: a naturalistic study of the effeciveness of trazodone in extended release formulation compared to SSRIs in patients with a major depressive disorder.Frontiers in pharmacology · 2023Article
- Polish adaptation of the Dimensional Anhedonia Rating Scale (DARS) - validation in the clinical sample.Frontiers in psychiatry · 2023Article
- Treating depression in clinical practice: new insights on the multidisciplinary use of trazodone.Frontiers in psychiatry · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
These are the preliminary results of a 12-week non-randomized, open-label, non-inferiority study comparing the effectiveness of trazodone in an extended-release formulation (XR) versus SSRIs in the treatment of major depressive disorder (MDD). Participants (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.