Evidence map›Paper›PMID 36672053›Full record

ArticleBrain sciences2022

Effectiveness of Anodal otDCS Following with Anodal tDCS Rather than tDCS Alone for Increasing of Relative Power of Intrinsic Matched EEG Bands in Rat Brains.

Nafe M Al-Tawarah, Zulal Kaptan, Hashem A Abu-Harirah, Mohammad Nofal, Belal Almajali, Sultan Jarrar, Zubeyir Bayraktaroğlu, Haitham Qaralleh, Khaled M Khleifat, Ziya Y Ziylan and 3 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Nafe M Al-TawarahDepartment of Medical Laboratory Sciences, Faculty of Science, Mutah University, Mutah 61710, Jordan.
Zulal KaptanDepartment of Physiology, Faculty of Medicine, Beykent University, Bolu 14030, Turkey.
Hashem A Abu-HarirahMedical Laboratory, Faculty of Allied Medical Sciences, Zarqa University, Zarqa 13110, Jordan.ORCID 0000-0003-1607-9051
Mohammad NofalDepartment of Surgery, Faculty of Medicine, Mutah University, Kerak 61710, Jordan.
Belal AlmajaliDepartment of Medical Laboratory Sciences, Faculty of Science, Mutah University, Mutah 61710, Jordan.ORCID 0000-0003-2879-9355
Sultan JarrarNeurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Zubeyir BayraktaroğluDepartment of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey.
Haitham QarallehDepartment of Medical Laboratory Sciences, Faculty of Science, Mutah University, Mutah 61710, Jordan.ORCID 0000-0002-9658-0040
Khaled M KhleifatDepartment of Medical Laboratory Sciences, Faculty of Science, Mutah University, Mutah 61710, Jordan.
Ziya Y ZiylanDepartment of Physiology, Faculty of Medicine, Beykent University, Bolu 14030, Turkey.
Rawand H Al DmourDepartment of Medical Laboratory Sciences, Faculty of Science, Mutah University, Mutah 61710, Jordan.
Moath AlqaralehPharmacological and Diagnostic Research Center (PDRC), Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19328, Jordan.
Sacit KaramurselDepartment of Physiology, Faculty of Medicine, Koc University, Istanbul 34450, Turkey.
Mutah University · JOBeykent University · TRAl-Ahliyya Amman University · JOIstanbul University · TRJordan University of Science and Technology · JOKoç University · TRZarqa University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study sought to determine whether (1) evidence is available of interactions between anodal tDCS and oscillated tDCS stimulation patterns to increase the power of endogenous brain oscillations and (2) the frequency matching the applied anodal otDCS's frequency and the brain's dominant intrinsic frequency influence power shifting during stimulation pattern sessions by both anodal DCS and anodal oscillated DCS.

methodRats received different anodal tDCS and otDCS stimulation patterns using 8.5 Hz and 13 Hz state-related dominant intrinsic frequencies of anodal otDCS. The rats were divided into groups with specific stimulation patterns: group A: tDCS-otDCS (8.5 Hz)-otDCS (13 Hz); group B: otDCS (8.5 Hz)-tDCS-otDCS (13 Hz); group C: otDCS (13 Hz)-tDCS-otDCS (8.5 Hz). Acute relative power changes (i.e., following 10 min stimulation sessions) in six frequency bands-delta (1.5-4 Hz), theta (4-7 Hz), alpha-1 (7-10 Hz), alpha-2 (10-12 Hz), beta-1 (12-15 Hz) and beta-2 (15-20 Hz)-were compared using three factors and repeated ANOVA measurement.

resultsFor each stimulation, tDCS increased theta power band and, above bands alpha and beta, a drop in delta power was observed. Anodal otDCS had a mild increasing power effect in both matched intrinsic and delta bands. In group pattern stimulations, increased power of endogenous frequencies matched exogenous otDCS frequencies-8.5 Hz or 13 Hz-with more potent effects in upper bands. The power was markedly more potent with the otDCS-tDCS stimulation pattern than the tDCS-otDCS pattern. SIGNIFICANCE: The findings suggest that the otDCS-tDCS pattern stimulation increased the power in matched intrinsic oscillations and, significantly, in the above bands in an ascending order. We provide evidence for the successful corporation between otDCS (as frequency-matched guidance) and tDCS (as a power generator) rather than tDCS alone when stimulating a desired brain intrinsic band (herein, tES specificity).

Indexed as

EEGfrontal cortexotDCSrelative band powertDCS

Identifiers

PMID36672053
PMCPMC9856406
OpenAlexW4313316819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.