Evidence map›Paper›PMID 36672045›Full record

ArticleBrain sciences2022

Alterations in Corticocortical Vestibular Network Functional Connectivity Are Associated with Decreased Balance Ability in Elderly Individuals with Mild Cognitive Impairment.

Rui Xia, Jinxin Ren, Xingjie Li, Jun Liu, Yalan Dai, Yuxing Kuang, Zhuguo Wu, Shangjie Chen

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rui XiaShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.ORCID 0000-0002-5941-8263
Jinxin RenThe Second School of Clinical Medicine, Guangdong Medical University, Dongguan 523808, China.
Xingjie LiShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.
Jun LiuShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.
Yalan DaiShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.ORCID 0000-0001-6629-7247
Yuxing KuangShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.
Zhuguo WuThe Second School of Clinical Medicine, Guangdong Medical University, Dongguan 523808, China.
Shangjie ChenShenzhen Bao'an Clinical Medical School, Guangdong Medical University, Shenzhen 518100, China.
Guangdong Medical College · CN

Funding

GuangDong Basic and Applied Basic Research Foundation 2021A1515110764Science and Technology Program of Shenzhen JCYJ20210324110809025Science and Technology Program of Shenzhen JCYJ20220530142806014
6 · The paper itself

Abstract

The corticocortical vestibular network (CVN) plays an important role in maintaining balance and stability. In order to clarify the specific relationship between the CVN and the balance ability of patients with mild cognitive impairment (MCI), we recruited 30 MCI patients in the community. According to age and sex, they were 1:1 matched to 30 older adults with normal cognitive function. We evaluated balance ability and performed MRI scanning in the two groups of participants. We analyzed functional connectivity within the CVN based on the region of interest. Then, we performed a Pearson correlation analysis between the functional connection and the Berg Balance Scale scores. The research results show that compared with the control group, there were three pairs of functional connections (hMST_R−Premotor_R, PFcm_R−SMA_L, and hMST_L−VIP_R) that were significantly decreased in the CVNs of the MCI group (p < 0.05). Further correlation analysis showed that there was a significant positive correlation between hMST_R−Premotor_R functional connectivity and BBS score (r = 0.364, p = 0.004). The decline in balance ability and increase in fall risk in patients with MCI may be closely related to the change in the internal connection mode of the corticocortical vestibular network.

Indexed as

balancecorticocortical vestibular networkfallfunctional connectionmild cognitive impairment

Identifiers

PMID36672045
PMCPMC9856347
OpenAlexW4313361458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.