Evidence map›Paper›PMID 36671871›Full record

ReviewBiosensors2022

Review: 3-Aminopropyltriethoxysilane (APTES) Deposition Methods on Oxide Surfaces in Solution and Vapor Phases for Biosensing Applications.

Marzhan Sypabekova, Aidan Hagemann, Donggee Rho, Seunghyun Kim

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  11. Just a little prick: careful cell contacts enabled by ceramic nanostraws.Pflugers Archiv : European journal of physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marzhan SypabekovaDepartment of Electrical & Computer Engineering, Baylor University, Waco, TX 76798, USA.
Aidan HagemannDepartment of Electrical & Computer Engineering, Baylor University, Waco, TX 76798, USA.
Donggee RhoCenter for Nano Bio Development, National NanoFab Center (NNFC), Daejeon 34141, Republic of Korea.
Seunghyun KimDepartment of Electrical & Computer Engineering, Baylor University, Waco, TX 76798, USA.ORCID 0000-0001-5950-7592

Funding

Development of a low cost, label-free, and highly sensitive optical cavity-based biosensor for point-of-care diagnosticsR15GM146233 · NIGMS · BAYLOR UNIVERSITY · PI KIM, SEUNGHYUN · 2022 to 2022
$420k
Nanomedical Devices Development in South Korea Project of NNFCNIH HHS R15GM146233
6 · The paper itself

Abstract

Surface functionalization and bioreceptor immobilization are critical processes in developing a highly sensitive and selective biosensor. The silanization process with 3-aminopropyltriethoxysilane (APTES) on oxide surfaces is frequently used for surface functionalization because of beneficial characteristics such as its bifunctional nature and low cost. Optimizing the deposition process of the APTES layer to obtain a monolayer is crucial to having a stable surface and effectively immobilizing the bioreceptors, which leads to the improved repeatability and sensitivity of the biosensor. This review provides an overview of APTES deposition methods, categorized into the solution-phase and vapor-phase, and a comprehensive summary and guide for creating stable APTES monolayers on oxide surfaces for biosensing applications. A brief explanation of APTES is introduced, and the APTES deposition methods with their pre/post-treatments and characterization results are discussed. Lastly, APTES deposition methods on nanoparticles used for biosensors are briefly described.

Indexed as

Biosensing TechniquesOxidesGasesPropylaminesSilanesSurface Propertiesamino-propyl-triethoxysilaneGasesOxidesPropylaminesSilanesAPTESbiosensorfunctionalizationmonolayeroxide surfacesilanization

Identifiers

PMID36671871
PMCPMC9856095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.