Evidence map›Paper›PMID 36671758›Full record

ArticleBiology2022

Measurement of Force and Intramuscular Pressure Changes Related to Thrust Spinal Manipulation in an In Vivo Animal Model.

William R Reed, Carla R Lima, Michael A K Liebschner, Christopher P Hurt, Peng Li, Maruti R Gudavalli

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

William R ReedDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-4580-485X
Carla R LimaRehabilitation Sciences Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Michael A K LiebschnerDepartment of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Christopher P HurtDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Peng LiSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-9026-9999
Maruti R GudavalliCollege of Chiropractic Medicine, Keiser University, West Palm Beach, FL 33411, USA.
University of Alabama at Birmingham · USBaylor College of Medicine · USKeiser University · US

Funding

Proprioceptive mechanisms underlying post-spinal manipulation response in an NGF-induced low back pain modelR21AT010517 · NCCIH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI REED, WILLIAM RAY · 2019 to 2020
$407k
NIH HHS R21AT010517
6 · The paper itself

Abstract

Current knowledge regarding biomechanical in vivo deep tissue measures related to spinal manipulation remain somewhat limited. More in vivo animal studies are needed to better understand the effects viscoelastic tissue properties (i.e., dampening) have on applied spinal manipulation forces. This new knowledge may eventually help to determine whether positive clinical outcomes are associated with particular force thresholds reaching superficial and/or deep spinal tissues. A computer-controlled feedback motor and a modified Activator V device with a dynamic load cell attached were used to deliver thrust spinal manipulations at various magnitudes to the L7 spinous process in deeply anesthetized animals. Miniature pressure catheters (Millar SPR-1000) were inserted unilaterally into superficial and deep multifidi muscles. Measurements of applied mechanical forces and superficial/deep multifidi intramuscular pressure changes were recorded during spinal manipulations delivered in vivo. Manipulative forces and net changes in intramuscular pressures reaching deep spinal tissues are greatly diminished by viscoelastic properties of in vivo tissues, which could have possible clinical safety and/or mechanistic implications.

Indexed as

biomechanicsforceintramuscularlumbarmanual therapymultifidusmusclespinal manipulationspineviscoelasticity

Identifiers

PMID36671758
PMCPMC9855381
OpenAlexW4313398449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.