Evidence map›Paper›PMID 36671755›Full record

ArticleBiology2022

Caffeine Delays Ethanol-Induced Sedation in

Sonia Tremblay, Yanqiqi Zeng, Aixin Yue, Kiana Chabot, Abigail Mynahan, Stephanie Desrochers, Sarra Bridges, S Tariq Ahmad

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Sonia TremblayDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Yanqiqi ZengDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Aixin YueDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Kiana ChabotDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Abigail MynahanDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Stephanie DesrochersDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Sarra BridgesDepartment of Biology, Colby College, Waterville, ME 04901, USA.
S Tariq AhmadDepartment of Biology, Colby College, Waterville, ME 04901, USA.
Colby College · USDartmouth College · USNew York Institute of Technology · USNorthwestern University · USUniversity of Colorado Boulder · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Colby College Science Division GrantNIGMS NIH HHS P20GM0103423NIGMS NIH HHS P20 GM103423
6 · The paper itself

Abstract

Caffeine and ethanol are among the most widely available and commonly consumed psychoactive substances. Both interact with adenosine receptor-mediated signaling which regulates numerous neurological processes including sleep and waking behaviors. In mammals, caffeine is an adenosine receptor antagonist and thus acts as a stimulant. Conversely, ethanol is a sedative because it promotes GABAergic neurotransmission, inhibits glutamatergic neurotransmission, and increases the amount of adenosine in the brain. Despite seemingly overlapping interactions, not much is known about the effect of caffeine on ethanol-induced sedation in

Indexed as

adenosine receptorcaffeineDrosophilaethanolsedation

Identifiers

PMID36671755
PMCPMC9855986
OpenAlexW4313362249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.