Evidence map›Paper›PMID 36671706›Full record

ArticleBiology2022

A Potential Negative Regulatory Function of Myostatin in the Growth of the Pacific Abalone,

Jianfang Huang, Mingcan Zhou, Jianming Chen, Caihuan Ke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jianfang HuangInstitute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, China.
Mingcan ZhouCollege of Ocean and Earth Sciences, Xiamen University, Xiamen 361102, China.
Jianming ChenInstitute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, China.
Caihuan KeCollege of Ocean and Earth Sciences, Xiamen University, Xiamen 361102, China.
Minjiang University · CNXiamen University · CN

Funding

Earmarked Fund for CARS No. CARS-49Fuzhou Science and Technology Planning Project of 2021-P-045Key S & T Program of Fujian Province No. 2020NZ08003Natural Science Foundation of Fujian Province 2021J05211Natural Science Foundation of Fujian Province 2022J05243Seed Industry Innovation and Industrialization in Fujian Province No.2021FJSCZY02Special Fund for Ocean and Fisheries of Xiamen No. 21CZY018HJ01Young and Middle-aged Teachers Education Scientific Research Project of Fujian Provincial Department of Education JAT210334
6 · The paper itself

Abstract

Myostatin, also known as GDF8, is a member of the transforming growth factor-β (TGF-β) superfamily. In vertebrates, myostatin negatively regulates the growth of skeletal muscle. In invertebrates, it has been reported to be closely related to animal growth. However, knowledge concerning the molecular mechanisms involved in the myostatin regulation of molluscan growth is limited. In this study, we found that the hdh-myostatin open reading frame (ORF) comprised 1470 base pairs that encoded 489 amino acids and contained structural characteristics typical of the TGF-β superfamily, including a C-terminal signal peptide, a propeptide domain, and TGF-β region. Gene expression analysis revealed that

Indexed as

Haliotis discus hannaimolluscan growthmyostatinRNA interferencesingle nucleotide polymorphism

Identifiers

PMID36671706
PMCPMC9854804
OpenAlexW4312187441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.