Evidence map›Paper›PMID 36671593›Full record

ReviewBioengineering (Basel, Switzerland)2022

Current Role of Intra-Articular Injections of Platelet-Rich Plasma in Adhesive Capsulitis of Shoulder: A Systematic Review.

Bushu Harna, Vijay Gupta, Shivali Arya, Naveen Jeyaraman, Ramya Lakshmi Rajendran, Madhan Jeyaraman, Prakash Gangadaran, Manish Khanna, Chae Moon Hong, Byeong-Cheol Ahn

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Bushu HarnaIndian Orthoapedic Rheumatology Association (IORA), Lucknow 226010, Uttar Pradesh, India.
Vijay GuptaIndian Orthoapedic Rheumatology Association (IORA), Lucknow 226010, Uttar Pradesh, India.
Shivali AryaDepartment of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Naveen JeyaramanIndian Orthoapedic Rheumatology Association (IORA), Lucknow 226010, Uttar Pradesh, India.ORCID 0000-0002-4362-3326
Ramya Lakshmi RajendranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea.ORCID 0000-0001-6987-0854
Madhan JeyaramanIndian Orthoapedic Rheumatology Association (IORA), Lucknow 226010, Uttar Pradesh, India.ORCID 0000-0002-9045-9493
Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea.ORCID 0000-0002-0658-4604
Manish KhannaIndian Orthoapedic Rheumatology Association (IORA), Lucknow 226010, Uttar Pradesh, India.
Chae Moon HongDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea.ORCID 0000-0002-5519-6982
Byeong-Cheol AhnDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea.ORCID 0000-0001-7700-3929
Kyungpook National University Hospital · KRIndian Medical Association · INDr. M.G.R. Educational and Research Institute · INMax Super Speciality Hospital · INPost Graduate Institute of Medical Education and Research · IN

Funding

National Research Foundation of Korea NRF-2021R1I1A1A01040732National Research Foundation of Korea NRF-2022R1I1A1A01068652
6 · The paper itself

Abstract

Adhesive capsulitis shoulder is a common problem of patients presenting with shoulder pain and disability. The approach to such patients includes a variety of modalities. This systematic review evaluates the efficacy of intra-articular injections of platelet-rich plasma (PRP) in the treatment. A literature search was performed between January 2010 and 30 May 2022. MeSH terms used were 'Platelet-rich plasma' OR 'PRP' AND 'Frozen shoulder' OR 'Adhesive capsulitis shoulder' OR 'Periarthritis shoulder'. The search included published articles in the English language involving human subjects. Studies evaluating other types of shoulder disorders, in vitro studies, review articles, animal-model studies, and pre-clinical trials were excluded. The data regarding study characteristics, efficacy, and safety outcomes were analyzed. A total of 11 studies with 347 patients over 10 years were finally included in this review. Most publications were in 2019 and 2020, mostly from India. This review included seven comparative studies, three case series, and one case report. In seven studies, a single intra-articular PRP injection was administered, whereas in the rest of the studies two or multiple injections were given. Only one study demonstrated an equivocal efficacy of PRP and steroid intra-articular injection. The rest all depicted better clinical and functional outcomes with the PRP injection. Only one study compared the outcomes of hydro-dissection treatment in adhesive capsulitis with the intra-articular PRP injection. The rest all either examined PRP alone or compared it with the steroid intra-articular injection. None of the studies showed any major side effects. The intra-articular injections of PRP in the management of adhesive capsulitis of the shoulder provide a new treatment approach. Further studies are required to ascertain the efficacy and safety of the PRP intraarticular injection as a management alternative in adhesive capsulitis.

Indexed as

adhesive capsulitisfrozen shoulderperiarthritis shoulderplatelet-rich plasmasteroid

Identifiers

PMID36671593
PMCPMC9854870
OpenAlexW4312100000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.