ArticleBioengineering (Basel, Switzerland)2022
Clinical Application of Bioresorbable, Synthetic, Electrospun Matrix in Wound Healing.
Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063694 (Prospective Randomized Controlled Trial Comparing Infection Rates and Wound Closure Following Transmetatarsal Amputation With Aid of Electrospun Fiber Matrix), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Randomized Controlled Trial Comparing Infection Rates and Wound Closure Following Transmetatarsal Amputation With Aid of Electrospun Fiber Matrix
Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Spatiotemporally controlled delivery of biological effectors from nanofiber scaffolds accelerates skin wound healing in porcine models.Science advances · 2025Article
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- Bioresorbable Materials for Wound Management.Biomimetics (Basel, Switzerland) · 2025Review
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- In vitro cytocompatibility of triclosan coated Polyglactin910 sutures.Journal of materials science. Materials in medicine · 2024Article
- Conductive and alignment-optimized porous fiber conduits with electrical stimulation for peripheral nerve regeneration.Materials today. Bio · 2024Article
- Histopathologic Analysis of a Recalcitrant Calcaneal Wound Treated Using a Synthetic Hybrid-scale Fiber Matrix.Plastic and reconstructive surgery. Global open · 2024Article
- Management of irradiated post-mastectomy wound dehiscence with synthetic electrospun fiber matrix: a case report.Frontiers in oncology · 2024Article
- Article
- Antimicrobial Effectiveness Testing of Resorbable Electrospun Fiber Matrix per United States Pharmacopeia (USP) <51>.Cureus · 2023Article
- Biomimetic Connection of Transcutaneous Implants with Skin.Advanced healthcare materials · 2023Article
- Determining the measurement accuracy in assessing the progress of wound healing.Postepy dermatologii i alergologii · 2023Article
- Assessment of the Efficiency of Measuring Foot and Ankle Edema with a 3D Portable Scanner.Bioengineering (Basel, Switzerland) · 2023Article
- Inflammatory Reaction and Formation of Adhesions after Intraperitoneal Application of Biological SIS Mesh.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrospun polymeric matrices have long been investigated as constructs for use in regenerative medicine, yet relatively few have been commercialized for human clinical use. In 2017, a novel electrospun matrix, composed of two synthetic biocompatible polymers, polyglactin 910 (PLGA 10:90) and polydioxanone (PDO) of varying pore and fiber sizes (i.e., hybrid-scale) was developed and cleared by the FDA for human clinical use. The present review aims to explain the mechanism of action and review the preclinical and clinical results to summarize the efficacy of the matrix across multiple use cases within the wound care setting, including an assessment of over 150 wounds of varying etiologies treated with the synthetic matrix. Clinical data demonstrated effective use of the synthetic hybrid-scale fiber matrix across a variety of wound etiologies, including diabetic foot and venous leg ulcers, pressure ulcers, burns, and surgical wounds. This review represents a comprehensive clinical demonstration of a synthetic, electrospun, hybrid-scale matrix and illustrates its value and versatility across multiple wound etiologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.