Evidence map›Paper›PMID 36671499›Full record

ReviewBiomolecules2023

Archaea as a Model System for Molecular Biology and Biotechnology.

Federica De Lise, Roberta Iacono, Marco Moracci, Andrea Strazzulli, Beatrice Cobucci-Ponzano

Abstract readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Effects of FermentedAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Biotechnological Applications of Archaea.Progress in molecular and subcellular biology · 2026
    Review
  5. Article
  6. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  7. Bacterioruberin (CNutrients · 2025
    Review
  8. Review
  9. Article
  10. Bio-adsorption of Fe (II) by dry biomass of metal-tolerant haloarchaeon Haloferax alexandrinus GUSF-1.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  11. Article
  12. Article
  13. Teaching old dogs new tricks: genetic engineering methanogens.Applied and environmental microbiology · 2024
    Review
  14. Halophilic archaea as tools for bioremediation technologies.Applied microbiology and biotechnology · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Federica De LiseInstitute of Biosciences and BioResources, National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-9614-9226
Roberta IaconoDepartment of Biology, University of Naples Federico II, Complesso Universitario di Monte S. Angelo, Via Cinthia 21, 80126 Naples, Italy.ORCID 0000-0002-3586-4322
Marco MoracciInstitute of Biosciences and BioResources, National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-9846-2531
Andrea StrazzulliDepartment of Biology, University of Naples Federico II, Complesso Universitario di Monte S. Angelo, Via Cinthia 21, 80126 Naples, Italy.ORCID 0000-0002-9690-149X
Beatrice Cobucci-PonzanoInstitute of Biosciences and BioResources, National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.

Funding

Agenzia Spaziale Italiana 2019-3-U.O.
6 · The paper itself

Abstract

Archaea represents the third domain of life, displaying a closer relationship with eukaryotes than bacteria. These microorganisms are valuable model systems for molecular biology and biotechnology. In fact, nowadays, methanogens, halophiles, thermophilic euryarchaeota, and crenarchaeota are the four groups of archaea for which genetic systems have been well established, making them suitable as model systems and allowing for the increasing study of archaeal genes' functions. Furthermore, thermophiles are used to explore several aspects of archaeal biology, such as stress responses, DNA replication and repair, transcription, translation and its regulation mechanisms, CRISPR systems, and carbon and energy metabolism. Extremophilic archaea also represent a valuable source of new biomolecules for biological and biotechnological applications, and there is growing interest in the development of engineered strains. In this review, we report on some of the most important aspects of the use of archaea as a model system for genetic evolution, the development of genetic tools, and their application for the elucidation of the basal molecular mechanisms in this domain of life. Furthermore, an overview on the discovery of new enzymes of biotechnological interest from archaea thriving in extreme environments is reported.

Indexed as

ArchaeaEuryarchaeotaBacteriaBiotechnologyMolecular BiologyarchaeaCAZymeshyperthermophilesmetagenomicmolecular biologyrecoding

Identifiers

PMID36671499
PMCPMC9855744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.