Evidence map›Paper›PMID 36671487›Full record

ArticleBiomolecules2023

Circ-CPSF1 Worsens Radiation-Induced Oxidative Stress Injury in

Jing Yuan, Fei Lin, Zhiyong Wu, Zhilin Jiang, Ting Wang, Sitong Huo, Weinan Lai, Li Li, Chao Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jing YuanSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Fei LinDepartment of Biochemistry and Molecular Biology, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Basic Medical Science, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0001-8344-2901
Zhiyong WuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Zhilin JiangThe First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China.
Ting WangDepartment of Biochemistry and Molecular Biology, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Basic Medical Science, Southern Medical University, Guangzhou 510515, China.
Sitong HuoSchool of Medicine, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-5402-8437
Weinan LaiDepartment of Rheumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Li LiCollege of Basic Medicine and Life Sciences, Hainan Medical University, Haikou 571199, China.
Chao ZhangNanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nanfang Hospital · CNCell Technology (China) · CNHainan Medical University · CNSouthern Medical University · CNTsinghua University · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2019A15151101590Guangzhou Basic and Applied Basic Research Project 202201011800National Natural Science Foundation of China 81872557Science Fundation of Guangdong Provincial Administration of Traditional Chinese Medicine 20201221the Key Research and Development Foundation of Hainan Province ZDYF2021SHFZ223
6 · The paper itself

Abstract

Radioactive substances have been used in various aspects in daily life. However, high-energy radiation could cause environmental problems, which would damage the human body. Circular RNA (CircRNA) has great potential in the minimization of ionizing radiation damage. To find a potential diagnostic and therapeutic target for reducing the damage of ionizing radiation, we selected circRNA cleavage and polyadenylation specificity factor subunit 1 (circ-CPSF1) based on its up-regulated expression after X-ray radiation and explored its effect on response to ionizing radiation using

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsApoptosisGene ExpressionHumansOxidative StressRNA, CircularCaenorhabditis elegans ProteinsRNA, Circularapoptosiscirc-CPSF1DNA damage response (DDR)radiation

Identifiers

PMID36671487
PMCPMC9856148
OpenAlexW4313494140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.