Evidence map›Paper›PMID 36671483›Full record

ArticleBiomolecules2023

Heparin-Induced Changes of Vascular Endothelial Growth Factor (VEGF

Ekaterina L Nemashkalova, Marina P Shevelyova, Andrey V Machulin, Dmitry D Lykoshin, Roman S Esipov, Evgenia I Deryusheva

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Inhibition of VEGFJournal of chemical information and modeling · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ekaterina L NemashkalovaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Pushchino 142290, Russia.
Marina P ShevelyovaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Pushchino 142290, Russia.
Andrey V MachulinSkryabin Institute of Biochemistry and Physiology of Microorganisms, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Pushchino 142290, Russia.ORCID 0000-0002-4859-7219
Dmitry D LykoshinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Roman S EsipovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Evgenia I DeryushevaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Pushchino 142290, Russia.
Institute for Biological Instrumentation · RUInstitute of Bioorganic Chemistry · RUG. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms · RU

Funding

Russian Science Foundation 22-24-00083
6 · The paper itself

Abstract

Vascular endothelial growth factor-A (VEGF-A), a secreted homodimeric glycoprotein, is a critical regulator of angiogenesis in normal and pathological states. The binding of heparin (HE) to VEGF

Indexed as

Receptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AHeparinHumansVascular Endothelial Growth FactorsHeparinReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth Factorsdifferential scanning calorimetryheparinprotein aggregationvascular endothelial growth factor

Identifiers

PMID36671483
PMCPMC9856036
OpenAlexW4313584127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.