Evidence map›Paper›PMID 36671453›Full record

ArticleBiomolecules2022

Metabolic Maturation Exaggerates Abnormal Calcium Handling in a

Robert J Barndt, Qing Liu, Ying Tang, Michael P Haugh, Jeffery Cui, Stephen Y Chan, Haodi Wu

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. The role of metal ions iron, copper, and zinc in the immune microenvironment of gastric cancer.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robert J BarndtPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Qing LiuDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA.
Ying TangPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Michael P HaughDepartment of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA 15213, USA.
Jeffery CuiDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Stephen Y ChanPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.ORCID 0000-0002-9520-7527
Haodi WuPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.ORCID 0000-0002-7900-3073
University of Pittsburgh · USCenter for Human Genetics · US

Funding

Defining the Complex Biology of the miR-130/301 Family in Pulmonary HypertensionR01HL124021 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y · 2014 to 2025
$4.9M
Iron-Sulfur Deficiency as a Critical Pathogenic Cause of Pulmonary HypertensionR01HL122596 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y · 2015 to 2024
$4.5M
BIOREPOSITORY OF HUMAN INDUCED PLURIPOTENT STEM CELLSFORCARDIOVASCULAR DISEASES (BHIPSC-CVD) - TASK AREA B75N92020D00019 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH · 2021 to 2024
$4.0M
Genetic and hypoxic control of a lncRNA axis orchestrates endothelial reprogramming in pulmonary hypertensionR01HL151228 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Stephen Y Chan · 2023 to 2026
$2.8M
Epigenetic regulation of PDE signaling in dilated cardiomyopathyR00HL133473 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WU, HAODI · 2021 to 2023
$747k
American Heart Association 18CDA34110128American Heart Association 18EIA33900027National Institute of Health HL 122596NHLBI NIH HHS 75N92020D00019NHLBI NIH HHS 75N92023D00019NHLBI NIH HHS R00 HL133473NHLBI NIH HHS R01 HL122596NHLBI NIH HHS R01 HL124021NHLBI NIH HHS R01 HL151228
6 · The paper itself

Abstract

Danon disease (DD) is caused by mutations of the gene encoding lysosomal-associated membrane protein type 2 (

Indexed as

Glycogen Storage Disease Type IIbInduced Pluripotent Stem CellsCalciumHumansLysosomal-Associated Membrane Protein 2Myocytes, CardiacReactive Oxygen SpeciesCalciumLAMP2 protein, humanLysosomal-Associated Membrane Protein 2Reactive Oxygen SpeciesarrhythmiaDanon diseaseiPSC-derived cardiomyocyteLAMP2metabolic maturation

Identifiers

PMID36671453
PMCPMC9855424
OpenAlexW4313319124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.