Evidence map›Paper›PMID 36671440›Full record

ReviewBiomolecules2022

Advances and Innovations of 3D Bioprinting Skin.

Moon Sung Kang, Jinju Jang, Hyo Jung Jo, Won-Hyeon Kim, Bongju Kim, Heoung-Jae Chun, Dohyung Lim, Dong-Wook Han

Abstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
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  8. Innovate to heal: 3D bioprinting tackles epidermolysis bullosa.Annals of medicine and surgery (2012) · 2025
    Article
  9. Review
  10. Review
  11. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  12. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Moon Sung KangDepartment of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Republic of Korea.
Jinju JangDepartment of Mechanical Engineering, Yonsei University, Seoul 03722, Republic of Korea.
Hyo Jung JoDepartment of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Republic of Korea.
Won-Hyeon KimDental Life Science Research Institute/Innovation Research & Support Center for Dental Science, Seoul National University Dental Hospital, Seoul 03080, Republic of Korea.ORCID 0000-0002-9742-7945
Bongju KimDental Life Science Research Institute/Innovation Research & Support Center for Dental Science, Seoul National University Dental Hospital, Seoul 03080, Republic of Korea.ORCID 0000-0001-7309-5977
Heoung-Jae ChunDepartment of Mechanical Engineering, Yonsei University, Seoul 03722, Republic of Korea.
Dohyung LimDepartment of Mechanical Engineering, Sejong University, Seoul 05006, Republic of Korea.ORCID 0000-0003-3752-7079
Dong-Wook HanDepartment of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-8314-1981

Funding

Ministry of Trade, Industry & Energy (MOTIE, Korea) 20014399National Research Foundation of Korea 2021R1A2C2006013
6 · The paper itself

Abstract

Three-dimensional (3D) bioprinted skin equivalents are highlighted as the new gold standard for alternative models to animal testing, as well as full-thickness wound healing. In this review, we focus on the advances and innovations of 3D bioprinting skin for skin regeneration, within the last five years. After a brief introduction to skin anatomy, 3D bioprinting methods and the remarkable features of recent studies are classified as advances in materials, structures, and functions. We will discuss several ways to improve the clinical potential of 3D bioprinted skin, with state-of-the-art printing technology and novel biomaterials. After the breakthrough in the bottleneck of the current studies, highly developed skin can be fabricated, comprising stratified epidermis, dermis, and hypodermis with blood vessels, nerves, muscles, and skin appendages. We hope that this review will be priming water for future research and clinical applications, that will guide us to break new ground for the next generation of skin regeneration.

Indexed as

BioprintingTissue EngineeringAnimalsEpidermisPrinting, Three-DimensionalSkin3D bioprintingbiomaterialsskin regenerationskin tissue engineeringwound healing

Identifiers

PMID36671440
PMCPMC9856167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.