Evidence map›Paper›PMID 36671404›Full record

ArticleBiomolecules2022

Differential Gene Expression Induced by Different TLR Agonists in A549 Lung Epithelial Cells Is Modulated by CRISPR Activation of TLR10.

Špela Knez, Mojca Narat, Jernej Ogorevc

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Updates on Toll-Like Receptor 10 Research.European journal of immunology · 2025
    Review
  2. The functional role of CST1 and CCL26 in asthma development.Immunity, inflammation and disease · 2024
    Article
  3. Article
  4. Frontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Špela KnezDepartment of Animal Science, Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Mojca NaratDepartment of Animal Science, Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Jernej OgorevcDepartment of Animal Science, Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7663-3566
University of Ljubljana · SI

Funding

Slovenian Research Agency 53632
6 · The paper itself

Abstract

Toll-like receptor 10 (TLR10) is the only member of the TLR family whose function and ligand have not been clearly described. Literature reports on its function are contradictory and suggest a possible immunomodulatory role that depends on the cell type, the pathogen, and the level of TLR10 expression. To investigate the regulatory role of TLR10 in A549 lung epithelial cells, we overexpressed

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCytokinesA549 CellsEpithelial CellsGene ExpressionHumansLungToll-Like Receptor 10CytokinesTLR10 protein, humanToll-Like Receptor 10CRISPR/dCas9cytokinesinflammationinnate immunitylung epitheliumTLR10

Identifiers

PMID36671404
PMCPMC9855645
OpenAlexW4312186361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.