Evidence map›Paper›PMID 36671393›Full record

ArticleBiomolecules2022

Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice.

Felicia N Watson, Caroline J Duncombe, Anya C Kalata, Ethan Conrad, Sumana Chakravarty, B Kim Lee Sim, Stephen L Hoffman, Moriya Tsuji, Melanie J Shears, Sean C Murphy

Abstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Felicia N WatsonGraduate Program in Pathobiology, Department of Global Health, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0003-1468-5648
Caroline J DuncombeGraduate Program in Pathobiology, Department of Global Health, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0002-4356-6317
Anya C KalataDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98109, USA.
Ethan ConradDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0002-2876-9845
Sumana ChakravartySanaria Inc., 9800 Medical Center Drive, Suite A209, Rockville, MD 20850, USA.
B Kim Lee SimSanaria Inc., 9800 Medical Center Drive, Suite A209, Rockville, MD 20850, USA.
Stephen L HoffmanSanaria Inc., 9800 Medical Center Drive, Suite A209, Rockville, MD 20850, USA.
Moriya TsujiAaron Diamond AIDS Research Center, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0001-8587-277X
Melanie J ShearsDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98109, USA.
Sean C MurphyGraduate Program in Pathobiology, Department of Global Health, University of Washington, Seattle, WA 98109, USA.

Funding

Liver resident memory for malariaR01AI141857 · NIAID · UNIVERSITY OF WASHINGTON · PI MURPHY, SEAN C · 2019 to 2023
$3.9M
Improving the Translational Potential of a Prime-and-Trap Malaria VaccineF31AI169754 · NIAID · UNIVERSITY OF WASHINGTON · PI WATSON, FELICIA · 2022 to 2023
$54k
NIAID NIH HHS F31 AI169754NIAID NIH HHS R01 AI141857NIH HHS 1F31AI169754-01NIH HHS 1R01AI141857
6 · The paper itself

Abstract

7DW8-5 is a potent glycolipid adjuvant that improves malaria vaccine efficacy in mice by inducing IFN-γ and increasing protective CD8

Indexed as

MalariaMalaria VaccinesAdjuvants, ImmunologicAdjuvants, PharmaceuticAnimalsCD8-Positive T-LymphocytesCytokinesFemaleGlycolipidsMaleMiceProtozoan ProteinsAdjuvants, ImmunologicAdjuvants, PharmaceuticCytokinesGlycolipidsMalaria VaccinesProtozoan Proteins7DW8-5adjuvantintradermalmalariaPlasmodiumsexsporozoitesvaccine

Identifiers

PMID36671393
PMCPMC9855660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.