Evidence map›Paper›PMID 36671388›Full record

ArticleBiomolecules2022

The Potential Utility of Circulating Oncofetal H19 Derived miR-675 Expression versus Tissue lncRNA-H19 Expression in Diagnosis and Prognosis of HCC in Egyptian Patients.

Shimaa Abdelsattar, Dina Sweed, Hala F M Kamel, Zeinab A Kasemy, Abdallah M Gameel, Hassan Elzohry, Omnia Ameen, Eman Ibrahim Elgizawy, Ahmed Sallam, Asmaa Mosbeh and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Shimaa AbdelsattarClinical Biochemistry and Molecular Diagnostics Department, National Liver Institute, Menofia University, Shebin El-Kom 32511, Egypt.ORCID 0000-0002-3993-5378
Dina SweedPathology Department, National Liver Institute, Menofia University, Shebin El-Kom 32511, Egypt.ORCID 0000-0001-6483-5056
Hala F M KamelDepartment of Biochemistry, Faculty of Medicine, Umm Al Qura University, Makka 21955, Saudi Arabia.ORCID 0000-0001-9960-4100
Zeinab A KasemyPublic Health and Community Medicine Department, Faculty of Medicine, Menofia University, Shebin El-Kom 32511, Egypt.
Abdallah M GameelClinical Pathology Department, National Cancer Institute, Cairo University, Cairo 11796, Egypt.ORCID 0000-0003-4632-015X
Hassan ElzohryHepatology and Gastroenterology Department, National Liver Institute, Menofia University, Shebin El-Kom 32511, Egypt.ORCID 0000-0001-6062-7954
Omnia AmeenPhysiology Department, Faculty of Medicine, Menofia University, Shebin El-Kom 32511, Egypt.
Eman Ibrahim ElgizawyPhysiology Department, Faculty of Medicine, Menofia University, Shebin El-Kom 32511, Egypt.
Ahmed SallamDepartment of Hepatobiliary and Pancreatic Surgery, National Liver Institute, Menofia University, Shebin El-Kom 32511, Egypt.
Asmaa MosbehPathology Department, National Liver Institute, Menofia University, Shebin El-Kom 32511, Egypt.
Mahmoud S AbdallahClinical Pharmacy Department, Faculty of Pharmacy, University of Sadat City (USC), Sadat City 32897, Egypt.ORCID 0000-0002-3237-1792
Fatma O KhalilClinical and Molecular Microbiology and Immunology Department, National Liver Institute, Menoufia University, Shebin El-Kom 32511, Egypt.ORCID 0000-0002-3157-5232
Hiba S Al-AmodiDepartment of Biochemistry, Faculty of Medicine, Umm Al Qura University, Makka 21955, Saudi Arabia.ORCID 0000-0003-1865-0004
Sally M El-HefnwayDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Menofia University, Shebin El-Kom 32511, Egypt.
Menoufia University · EGAin Shams University · EGCairo University · EGUmm al-Qura University · SAUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Interestingly, lncRNA-H19 acts independently in HCC and influences miR-675 expressions. We aimed to assess the potential utility of tissue lncRNA-H19 versus miR-675 expressions as a non-invasive biomarker for HCC diagnosis and prognosis in Egyptian patients. Ninety-one HCC patients and 91 controls included in this study were investigated for expression of lncRNA-H19 and miR675 using RT-qPCR. Our results showed that the expression of lncRNA-H19 and microRNA-675 were higher in patients than in controls (

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsRNA, Long NoncodingEgyptGene Expression Regulation, NeoplasticHumansMicroRNAsMIRN675 microRNA, humanRNA, Long Noncodinghepatocellular carcinoma (HCC)long noncoding RNA-H19 (lnRNAs-H19)microRNA (miR-675)real-time quantitative reverse transcription PCR (RT-qPCR)

Identifiers

PMID36671388
PMCPMC9856163
OpenAlexW4311963740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.