Evidence map›Paper›PMID 36671376›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Impact of the Duration of Postoperative Antibiotics on the Prognosis of Patients with Infective Endocarditis.

Jinnam Kim, Jung Ho Kim, Hi Jae Lee, Se Ju Lee, Changhyup Kim, Jung Ah Lee, Ki Hyun Lee, Won Kyung Pyo, Jin Young Ahn, Su Jin Jeong and 4 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Perioperative care in infective endocarditis.Indian journal of thoracic and cardiovascular surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jinnam KimDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1310-6421
Jung Ho KimDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-5033-3482
Hi Jae LeeDepartment of Cardiovascular Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Se Ju LeeDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-9779-5062
Changhyup KimDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jung Ah LeeDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Ki Hyun LeeDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-3138-6685
Won Kyung PyoDepartment of Cardiovascular Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jin Young AhnDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Su Jin JeongDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-4025-4542
Nam Su KuDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-9717-4327
Seung Hyun LeeDepartment of Cardiovascular Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jun Yong ChoiDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-2775-3315
Joon-Sup YeomDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-8940-7170

Funding

National Research Foundation of Korea 2022R1C1C1010012
6 · The paper itself

Abstract

Appropriate postoperative antibiotic treatment in patients with infective endocarditis (IE) reduces the risks of recurrence and mortality. However, concerns about adverse drug reactions arise due to prolonged antibiotic usage. Therefore, we compared the recurrence and mortality rates according to the duration of postoperative antibiotic therapy in patients with IE. From 2005 to 2017, we retrospectively reviewed 416 patients with IE treated at a tertiary hospital in South Korea; among these, 216 patients who underwent heart valve surgery and received appropriate antibiotics were enrolled. The patients were divided into two groups based on the duration of usage of postoperative antibiotic therapy; the duration of postoperative antibiotic therapy was more than two weeks in 156 patients (72.2%) and two weeks or less in 60 patients (27.8%). The primary endpoint was IE relapse. The secondary endpoints were 1-year IE recurrence, 1-year mortality, and postoperative complication rates. The median age was 53 (interquartile range: 38-62) years. The relapse rate of IE was 0.9% (2/216). There was no statistical difference in relapse (0.0% vs. 1.3%,

Indexed as

durationinfective endocarditismortalitypostoperative antibiotic therapyrecurrencerelapse

Identifiers

PMID36671376
PMCPMC9854446

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.