Evidence map›Paper›PMID 36671281›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Cumulative Antibiogram: A Rapid Method to Hinder Transmission of Resistant Bacteria to Oral Cavity of Newborn Babies.

Mădălina Adriana Malița, Loredana Sabina Cornelia Manolescu, Cristina Florentina Pîrvu, Radu Catalin Costea, Elena Cristina Marcov, Mihai Burlibasa, Daniela Aurelia Pîrvu, Liliana Burlibașa, Mihaela Corina Radu, Irina Prasacu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mădălina Adriana MalițaDepartment of Dental Technology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Loredana Sabina Cornelia ManolescuDepartment of Microbiology, Parasitology and Virology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-8694-6195
Cristina Florentina PîrvuDepartment of Scientific Research Methodology-Ergonomics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 0102210 Bucharest, Romania.
Radu Catalin CosteaDepartment of Dental Technology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Elena Cristina MarcovDepartment of Restorative Dentistry, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 0102210 Bucharest, Romania.
Mihai BurlibasaDepartment of Dental Technology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Daniela Aurelia PîrvuDepartment of Dental Prostheses, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 0102210 Bucharest, Romania.
Liliana BurlibașaDepartment of Genetics, Faculty of Biology, University of Bucharest, 060101 Bucharest, Romania.ORCID 0000-0003-0596-9331
Mihaela Corina RaduDepartment of Birth, Obstetrics and Gynecology Hospital, 100409 Ploiesti, Romania.ORCID 0000-0002-8799-4831
Irina PrasacuDepartment of Fundamental Sciences, Faculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Viorel Ștefan PerieanuDepartment of Dental Technology, Faculty of Midwifery and Nursing, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA rapid bacterial diagnostic is needed more and more in the treatment of patients, because of the emergence of antibiotic resistance. The cumulative antibiogram, an annual report that monitors antimicrobial resistance trends in health care facilities, may provide a profile of empirical therapy useful in diverse emergency situations, such as transmission of resistant bacteria to oral cavity of newborn babies. We aimed to draw a profile of antibiotic resistance encountered.

methodsWe assessed the antibiotic resistance (ABR) profile in childbearing women and newborn babies in Ploiesti Obstetrics and Gynecology Hospital by the disk diffusion method characterizing the multidrug-resistant organisms after isolation and identification by phenotypic tests. Extended-spectrum β-lactamase (ESBL)-producing Enterobacterales (ESBL-E), Carbapenem-resistant Enterobacterales (CRE), vancomycin-resistant Enterococci (VRE), methicillin-resistant

resultsThe prevalence of antibiotic resistance was 11.32% (53/468), while the prevalence of the ESBL-E, MRSA, VRE and VR-GBS strains was 8.34% (39/468). Within the bacteria isolated from fifty-three childbearing women, the prevalence of ESBL-E, MRSA, VRE and VR-GBS was 22.64% (12/53), 32.08% (17/53), 11.32% (6/53) and 7.55% (4/53). In the whole studied group, the prevalence was 2.56% (12/468), 3.63% (17/468), 1.28% (6/468) and 0.86% (4/468). Resistant bacteria were detected at birth in the oral cavity of the newborn babies in all cases. Maternal and neonatal isolates shared similar characteristics.

conclusionsCumulative antibiogram is useful in case of empiric treatment needed in diverse emergencies, such as transmission of resistant bacteria to oral cavity of newborn babies.

Indexed as

antibiotic susceptibility testingcumulative antibiogrammaternal-to-neonate transmission

Identifiers

PMID36671281
PMCPMC9854765
OpenAlexW4313515828

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.