Evidence map›Paper›PMID 36671262›Full record

ArticleAntibiotics (Basel, Switzerland)2022

QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against

Jhesua Valencia, Vivian Rubio, Gloria Puerto, Luisa Vasquez, Anthony Bernal, José R Mora, Sebastian A Cuesta, José Luis Paz, Braulio Insuasty, Rodrigo Abonia and 6 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. DFT Study of Functionalized Benzoxazole-Based D-Molecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Chalcones as Emerging Antibacterial Scaffolds: A Mini Review.Mini reviews in medicinal chemistry · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jhesua ValenciaGrupo de Investigación en Química y Biología, Universidad del Norte, Km 5 vía Puerto Colombia, Barranquilla 081007, Colombia.
Vivian RubioGrupo de Micobacterias, Red TB Colombia, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá 111321, Colombia.ORCID 0000-0002-7487-1891
Gloria PuertoGrupo de Micobacterias, Red TB Colombia, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá 111321, Colombia.ORCID 0000-0002-8577-0228
Luisa VasquezGrupo de Micobacterias, Red TB Colombia, Dirección de Investigación en Salud Pública, Instituto Nacional de Salud, Bogotá 111321, Colombia.
Anthony BernalGrupo de Investigación en Química y Biología, Universidad del Norte, Km 5 vía Puerto Colombia, Barranquilla 081007, Colombia.
José R MoraGrupo de Química Computacional y Teórica (QCT-USFQ), Departamento de Ingeniería Química, Universidad San Francisco de Quito, Diego de Robles y Vía Interoceánica, Quito 170157, Ecuador.ORCID 0000-0001-6128-9504
Sebastian A CuestaGrupo de Química Computacional y Teórica (QCT-USFQ), Departamento de Ingeniería Química, Universidad San Francisco de Quito, Diego de Robles y Vía Interoceánica, Quito 170157, Ecuador.
José Luis PazDepartamento Académico de Química Inorgánica, Facultad de Química e Ingeniería Química, Universidad Nacional Mayor de San Marcos, Cercado de Lima 15081, Peru.ORCID 0000-0002-6177-7919
Braulio InsuastyResearch Group of Heterocyclic Compounds, Department of Chemistry, Universidad del Valle, A. A., Cali 25360, Colombia.ORCID 0000-0001-8371-3310
Rodrigo AboniaResearch Group of Heterocyclic Compounds, Department of Chemistry, Universidad del Valle, A. A., Cali 25360, Colombia.ORCID 0000-0003-3256-0961
Jairo QuirogaResearch Group of Heterocyclic Compounds, Department of Chemistry, Universidad del Valle, A. A., Cali 25360, Colombia.ORCID 0000-0002-9451-3063
Alberto InsuastyGrupo de Investigación en Materiales Funcionales Nanoestructurados, Universidad CESMAG, Pasto 520003, Colombia.
Andres ConeoMedicine Department, Division of Health Sciences, Universidad del Norte, Barranquilla 081007, Colombia.ORCID 0000-0001-6952-7570
Oscar VidalMedicine Department, Division of Health Sciences, Universidad del Norte, Barranquilla 081007, Colombia.ORCID 0000-0002-7807-1242
Edgar MárquezGrupo de Investigación en Química y Biología, Universidad del Norte, Km 5 vía Puerto Colombia, Barranquilla 081007, Colombia.ORCID 0000-0002-7503-1528
Daniel InsuastyGrupo de Investigación en Química y Biología, Universidad del Norte, Km 5 vía Puerto Colombia, Barranquilla 081007, Colombia.ORCID 0000-0001-9662-9505

Funding

Colciencias 201477758055 201477758055 (contract. No. 777 de 2018)
6 · The paper itself

Abstract

In this study, a series of novel quinolinone-based thiosemicarbazones were designed in silico and their activities tested in vitro against

Indexed as

dockingmolecular dynamics and cytotoxicityMycobacterium tuberculosisQSARquinolinonethiosemicarbazone

Identifiers

PMID36671262
PMCPMC9854539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.