Evidence map›Paper›PMID 36671249›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Antifungal and Immunomodulatory Ingredients from Traditional Chinese Medicine.

Hua Zhong, Lei Han, Ren-Yi Lu, Yan Wang

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Overview of Research on Essential Oils ofPharmaceuticals (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Frontiers in microbiology · 2024
    Article
  13. Synthetic Biology Facilitates Antimicrobials Discovery.Antibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hua ZhongSchool of Pharmacy, Second Military Medical University, Shanghai 200433, China.ORCID 0000-0003-0031-5283
Lei HanSchool of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Ren-Yi LuSchool of Pharmacy, Second Military Medical University, Shanghai 200433, China.ORCID 0000-0001-6539-8089
Yan WangSchool of Pharmacy, Second Military Medical University, Shanghai 200433, China.ORCID 0000-0003-1084-1957

Funding

National Natural Science Foundation of China 81772124National Natural Science Foundation of China 82204470the biosafety program of the National Natural Science Foundation of China 20SWAQX29-1-6
6 · The paper itself

Abstract

Fungal infections have become a growing public health challenge due to the clinical transmission of pathogenic fungi. The currently available antifungal drugs leave very limited choices for clinical physicians to deal with such situation, not to mention the long-standing problems of emerging drug resistance, side effects and heavy economic burdens imposed to patients. Therefore, new antifungal drugs are urgently needed. Screening drugs from natural products and using synthetic biology strategies are very promising for antifungal drug development. Chinese medicine is a vast library of natural products of biologically active molecules. According to traditional Chinese medicine (TCM) theory, preparations used to treat fungal diseases usually have antifungal and immunomodulatory functions. This suggests that if antifungal drugs are used in combination with immunomodulatory drugs, better results may be achieved. Studies have shown that the active components of TCM have strong antifungal or immunomodulatory effects and have broad application prospects. In this paper, the latest research progress of antifungal and immunomodulatory components of TCM is reviewed and discussed, hoping to provide inspiration for the design of novel antifungal compounds and to open up new horizons for antifungal treatment strategies.

Indexed as

antifungal drugcombination of drugsfungal infectionimmune regulationnatural producttraditional Chinese medicine

Identifiers

PMID36671249
PMCPMC9855100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.