Evidence map›Paper›PMID 36671038›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Vitiligo and Mental Health: Natural Compounds' Usefulness.

Luca Di Bartolomeo, Paolo Custurone, Natasha Irrera, Francesco Borgia, Federico Vaccaro, Francesco Squadrito, Mario Vaccaro

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Correlation Between the Koebner Phenomenon and Clinical Features in Vitiligo.Clinical, cosmetic and investigational dermatology · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Luca Di BartolomeoDepartment of Clinical and Experimental Medicine, Dermatology, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-5457-6246
Paolo CusturoneDepartment of Clinical and Experimental Medicine, Dermatology, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-2142-5054
Natasha IrreraDepartment of Clinical and Experimental Medicine, Pharmacology, University of Messina, 98125 Messina, Italy.
Francesco BorgiaDepartment of Clinical and Experimental Medicine, Dermatology, University of Messina, 98125 Messina, Italy.ORCID 0000-0003-3515-8441
Federico VaccaroDepartment of Dermatology, University of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0002-1745-4338
Francesco SquadritoDepartment of Clinical and Experimental Medicine, Pharmacology, University of Messina, 98125 Messina, Italy.
Mario VaccaroDepartment of Clinical and Experimental Medicine, Dermatology, University of Messina, 98125 Messina, Italy.ORCID 0000-0003-3787-5145
University of Messina · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitiligo is an autoimmune dermatosis frequently associated with other comorbidities, such as mental health disorders. It is unclear if vitiligo triggers mental disorders or if mental disorders trigger vitiligo, but each one affects and worsen the other, if present at the same time. Both mental health disorders and vitiligo present a multifactorial pathogenesis and often require prolonged periods of therapy, sometimes with poor results. Given the possible link of common pathogenetic factors and the need of integrated therapies, the aim of this review is to look at natural compounds as possible supplements for both conditions. The results yielded show a possible role of these supplements in ameliorating both conditions, thus helping these patients to achieve a better quality of life and reduce the need for prolonged therapies. The limitations regarding the relative lack of in vivo studies, and the increasing need to lighten the burden of these chronic diseases, suggests that it is mandatory to proceed with further trials.

Indexed as

antioxidantsanxietydepressiondermatosismental healthnatural compoundsobsessive compulsive disorderoxidative stresssupplementvitiligo

Identifiers

PMID36671038
PMCPMC9854903
OpenAlexW4315781539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.