Evidence map›Paper›PMID 36671003›Full record

ArticleAntioxidants (Basel, Switzerland)2023

P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types.

Ponarulselvam Sekar, George Hsiao, Yuan-Shen Chen, Wan-Wan Lin, Chi-Ming Chan

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. DoesJournal of evidence-based integrative medicine
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Role of P2X7R in Retinal Diseases: A Review.Immunity, inflammation and disease · 2025
    Review
  8. Article
  9. Protective effects of CY-09 and astaxanthin on NaIOInternational journal of ophthalmology · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ponarulselvam SekarGraduate Institute of Medical Sciences, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0003-4282-2865
George HsiaoDepartment of Pharmacology, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0001-9079-3646
Yuan-Shen ChenDepartment of Neurosurgery, National Taiwan University, Yunlin Branch, Yunlin County 640203, Taiwan.
Wan-Wan LinGraduate Institute of Medical Sciences, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-3207-734X
Chi-Ming ChanDepartment of Ophthalmology, Cardinal Tien Hospital, New Taipei City 23148, Taiwan.
National Taiwan University · TWFu Jen Catholic University · TWTaipei Medical University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 110-2314-B-567 - 003 - MY3; NSCCMOH-145-61National Taiwan University NTUHYL109.S010
6 · The paper itself

Abstract

Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO

Indexed as

microgliaP2X7photoreceptorsretinopathysodium iodate

Identifiers

PMID36671003
PMCPMC9854982
OpenAlexW4313824771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.