Evidence map›Paper›PMID 36670999›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Antioxidants in Sunscreens: Which and What For?

Ana Jesus, Sandra Mota, Ana Torres, Maria T Cruz, Emília Sousa, Isabel F Almeida, Honorina Cidade

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Review
  6. What's New in Photoprotection?American journal of clinical dermatology · 2026
    Review
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  8. Article
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  11. Review
  12. Article
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  15. Article
  16. Antioxidants (Basel, Switzerland) · 2025
    Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ana JesusAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-7425-9750
Sandra MotaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-5348-8431
Ana TorresAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-6077-3580
Maria T CruzFaculty of Pharmacy, University of Coimbra, 3004-531 Coimbra, Portugal.ORCID 0000-0001-9846-6754
Emília SousaLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-5397-4672
Isabel F AlmeidaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-1498-048X
Honorina CidadeLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0003-0715-1779
Universidade do Porto · PTCentro de Neurociências e Biologia Celular · PT

Funding

ERDF - European Regional Development Fund Centro 2020 Regional Operational Programme under project CENTRO-01-0145-FEDER-000012 (HealthyAging2020) and through the Northern Regional Operational Program (NORTE2020) under the project 47239 - Cork2Cosmetic (NORTE-01-0247-FEDER-047239).FCT-Fundação para a Ciência e a Tecnologia Ana Jesus acknowledges her PhD grant (UI/BD/151319/2021), and Sandra Mota and Ana Torres acknowledge their research fellowship (NORTE-01-0247-FEDER-047239)FCT-Fundação para a Ciência e a Tecnologia, I.P. project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Bio-sciences-UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy-i4HB.FCT-Fundação para a Ciência e a Tecnologia, I.P. UIDB/04423/2020, UIDP/04539/2020, UIDP/04423/2020 (Group of Natural Products and Medic-inal Chemistry-CIIMAR), as well as a structured program of R&D&I ATLANTIDA (NORTE-01-0145-FEDER-000040), supported by NORTE2020, through ERDF.
6 · The paper itself

Abstract

Ultraviolet (UV) radiation promotes the generation of reactive oxygen species (ROS) and nitrogen species (RNS), resulting in skin damage. Cosmetic industries have adopted a strategy to incorporate antioxidants in sunscreen formulations to prevent or minimize UV-induced oxidative damage, boost photoprotection effectiveness, and mitigate skin photoaging. Many antioxidants are naturally derived, mainly from terrestrial plants; however, marine organisms have been increasingly explored as a source of new potent antioxidant molecules. This work aims to characterize the frequency of the use of antioxidants in commercial sunscreens. Photoprotective formulations currently marketed in parapharmacies and pharmacies were analyzed with respect to the composition described on the label. As a result, pure compounds with antioxidant activity were found. The majority of sunscreen formulations contained antioxidants, with vitamin E and its derivatives the most frequent. A more thorough analysis of these antioxidants is also provided, unveiling the top antioxidant ingredients found in sunscreens. A critical appraisal of the scientific evidence regarding their effectiveness is also performed. In conclusion, this work provides an up-to-date overview of the use of antioxidants in commercial sunscreens for a better understanding of the advantages associated with their use in photoprotective formulations.

Indexed as

antioxidantsphotoprotectionscientific evidencesunscreenstrends

Identifiers

PMID36670999
PMCPMC9854756
OpenAlexW4313640343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.