Evidence map›Paper›PMID 36670990›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer.

Sandra Lucía Teniente, Adriana Carolina Flores-Gallegos, Sandra Cecilia Esparza-González, Lizeth Guadalupe Campos-Múzquiz, Sendar Daniel Nery-Flores, Raul Rodríguez-Herrera

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Natural based FeBMC chemistry · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Antimicrobial efficacy ofFrontiers in microbiology · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra Lucía TenienteFood Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and José Cárdenas, República Oriente, Saltillo 25280, Coahuila, Mexico.ORCID 0000-0003-1705-485X
Adriana Carolina Flores-GallegosFood Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and José Cárdenas, República Oriente, Saltillo 25280, Coahuila, Mexico.ORCID 0000-0001-5092-1404
Sandra Cecilia Esparza-GonzálezSchool of Dentistry, Universidad Autónoma de Coahuila, Dra. Cuquita Cepeda de Dávila Ave, Adolfo López Mateos, Saltillo 25125, Coahuila, Mexico.
Lizeth Guadalupe Campos-MúzquizFood Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and José Cárdenas, República Oriente, Saltillo 25280, Coahuila, Mexico.ORCID 0000-0002-7507-0885
Sendar Daniel Nery-FloresFood Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and José Cárdenas, República Oriente, Saltillo 25280, Coahuila, Mexico.ORCID 0000-0003-0739-2230
Raul Rodríguez-HerreraFood Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and José Cárdenas, República Oriente, Saltillo 25280, Coahuila, Mexico.ORCID 0000-0002-6428-4925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols are a broad group of bioactive phytochemicals with powerful antioxidant, anti-inflammatory, immunomodulatory, and antiviral activities. Numerous studies have demonstrated that polyphenol extracts obtained from natural sources can be used for the prevention and treatment of cancer. Pomegranate peel extract is an excellent source of polyphenols, such as punicalagin, punicalin, ellagic acid, and caffeic acid, among others. These phenolic compounds have antineoplastic activity in in vitro models of cervical cancer through the regulation of cellular redox balance, induction of apoptosis, cell cycle arrest, and modulation of different signaling pathways. The current review summarizes recent data from scientific reports that address the anticancer activity of the predominant polyphenol compounds present in PPE and their different mechanisms of action in cervical cancer models.

Indexed as

anticancerantiproliferationapoptosiscell cycle arrestcervical cancerpomegranate peelROS

Identifiers

PMID36670990
PMCPMC9854619

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.