ReviewAnimals : an open access journal from MDPI2023
Biomarkers of Intestinal Injury in Colic.
Review in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Serial Postoperative Blood and Peritoneal Fluid Analysis and Ultrasonographic Assessment in Client-Owned Horses Undergoing Ventral Midline Exploratory Celiotomy for Colic.Animals : an open access journal from MDPI · 2026Article
- New Diagnostic Score for Sepsis in Adult Horses with Acute Gastrointestinal Disease.Animals : an open access journal from MDPI · 2026Article
- Prognostic Significance of Erythrocyte Sedimentation Rate for Survival in Equine Colic.Animals : an open access journal from MDPI · 2026Article
- Evaluation of oxidative stress and antioxidant defense biomarkers in healthy and colic horses: correlation with type of colic and outcome.Journal of veterinary internal medicine · 2026Article
- Editorial: Biomarker identification and novel therapies in equine medicine.Frontiers in veterinary science · 2026Article
- The importance of prebiotics in managing colic in horses: focus onFrontiers in veterinary science · 2026Review
- Diagnostic performance of specific oxidative stress biomarkers, acute phase proteins, and certain trace elements in different severities of equine colic.Journal of equine science · 2025Article
- Equine colic: A comprehensive overview of the sonographic evaluation, diagnostic criteria, and management of different categories.Open veterinary journal · 2025Review
- Alactic base excess is not a sensitive or specific diagnostic tool for outcome in horses with colic.Frontiers in veterinary science · 2025Article
- Extracted Plasma Cell-Free DNA Concentrations Are Elevated in Colic Patients with Systemic Inflammation.Veterinary sciences · 2024Article
- A Comparative Review of Cytokines and Cytokine Targeting in Sepsis: From Humans to Horses.Cells · 2024Review
- Evaluation of Blood Lactate, Heart Rate, Blood Pressure, and Shock Index, and Their Association with Prognosis in Calves.Veterinary sciences · 2024Article
- Fecal Secretory Immunoglobulin A and Lactate Level as a Biomarker of Mucosal Immune Dysfunction in Horses With Colic.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Biomarkers are typically proteins, enzymes, or other molecular changes that are elevated or decreased in body fluids during the course of inflammation or disease. Biomarkers pose an extremely attractive tool for establishing diagnoses and prognoses of equine gastrointestinal colic, one of the most prevalent causes of morbidity and mortality in horses. This topic has received increasing attention because early diagnosis of some forms of severe colic, such as intestinal ischemia, would create opportunities for rapid interventions that would likely improve case outcomes. This review explores biomarkers currently used in equine medicine for colic, including acute phase proteins, proinflammatory cytokines, markers of endotoxemia, and tissue injury metabolites. To date, no single biomarker has been identified that is perfectly sensitive and specific for intestinal ischemia; however, L-lactate has been proven to be a very functional and highly utilized diagnostic tool. However, further exploration of other biomarkers discussed in this review may provide the key to accelerated identification, intervention, and better outcomes for horses suffering from severe colic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.