Evidence map›Paper›PMID 36670749›Full record

ArticleAnimals : an open access journal from MDPI2023

Adaptive Evolution of the OAS Gene Family Provides New Insights into the Antiviral Ability of Laurasiatherian Mammals.

Gang Liu, Xiaoyang Wu, Yongquan Shang, Xibao Wang, Shengyang Zhou, Honghai Zhang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gang LiuCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.ORCID 0000-0003-0730-7374
Xiaoyang WuCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.
Yongquan ShangCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.
Xibao WangCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.ORCID 0000-0002-2036-5184
Shengyang ZhouCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.
Honghai ZhangCollege of Life Sciences, Qufu Normal University, Qufu 273165, China.
Qufu Normal University · CN

Funding

China Postdoctoral Science Foundation 022M711884National Natural Science Foundation of China 31872242National Natural Science Foundation of China 32001228National Natural Science Foundation of China 32070405
6 · The paper itself

Abstract

Many mammals risk damage from virus invasion due to frequent environmental changes. The oligoadenylate synthesis (OAS) gene family, which is an important component of the immune system, provides an essential response to the antiviral activities of interferons by regulating immune signal pathways. However, little is known about the evolutionary characteristics of OASs in Laurasiatherian mammals. Here, we examined the evolution of the OAS genes in 64 mammals to explore the accompanying molecular mechanisms of the antiviral ability of Laurasiatherian mammals living in different environments. We found that

Indexed as

antiviralevolutionLaurasiatherian mammalsOAS gene family

Identifiers

PMID36670749
PMCPMC9854896
OpenAlexW4313640401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.