Evidence map›Paper›PMID 36670735›Full record

ArticleAnimals : an open access journal from MDPI2023

Effects of the Expressions and Variants of the

Xin Guo, Terigele Li, Datong Lu, Takahisa Yamada, Xihe Li, Siqin Bao, Jiasen Liu, Gerelt Borjigin, Ming Cang, Bin Tong

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Detection of theAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Relationship Between Breed,Animals : an open access journal from MDPI · 2025
    Article
  6. Article
  7. Effect ofAnimals : an open access journal from MDPI · 2025
    Article
  8. Review
  9. Polymorphisms in the 3'UTR of theFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin GuoThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.
Terigele LiInner Mongolia Agriculture Animal Husbandry Fishery and Biology Experiment Research Centre, Inner Mongolia Agricultural University, Hohhot 010010, China.
Datong LuThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.
Takahisa YamadaDepartment of Agrobiology, Faculty of Agriculture, Niigata University, Niigata 950-2181, Japan.
Xihe LiThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.ORCID 0000-0002-7001-7997
Siqin BaoThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.ORCID 0000-0002-9582-3194
Jiasen LiuInstitute of Animal Science, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot 010031, China.
Gerelt BorjiginCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010010, China.
Ming CangThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.
Bin TongThe State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010021, China.ORCID 0000-0003-4170-8737

Funding

the "Grassland Meritocrat" Scholars Program of the Inner Mongolia Autonomous Region of China No. CYYC6068the High Level Overseas Talents Project from the Ministry of Human Resources and Social Security of China [2018] No. 190the High-level Talents Import Program of Inner Mongolia University of China No. 21400-5165112the Inner Mongolia Science & Technology Plan of China No. 2019ZD08 and 2020ZD0007the State Key Laboratory for Reproductive Regulation and Breeding of Grassland Livestock of China No. 2019ZD031 and 2021ZZ0204the Xilingol Science & Technology Plan of China No. 202002 and 202120
6 · The paper itself

Abstract

Fatty acid (FA) composition has an important impact on the nutrition and flavor of meat, and on consumer health, and is receiving more attention in the sheep industry. This study aimed to evaluate the relationship between the expression levels of the CAST gene and the FA composition in the longissimus thoracis (LL) muscle, to identify novel variants of CAST, and to perform association analysis with the FA composition in grazing Sonid lambs. The correlation results showed that high expression levels of CAST are correlated with better FA compositions and classes in LL. For association studies, the results showed that c.1210C>T and c.1437G>A in LD-M, and c.2097C>T mutations are associated with some compositions and classes of FA in the LL of grazing Sonid sheep. Two missense c.646G>C (G216R) and c.1210C>T (R404C) mutations were predicted to influence the Calpain_inhib domains of CAST. Thus, the correlation results and associated mutations are expected to be genetic selection markers for the FA composition and meat quality of grazing Sonid lamb muscle and provide new insights into sheep meat quality traits influenced by the ovine CAST gene.

Indexed as

associationCAST geneexpressionfatty acidSonid sheepvariants

Identifiers

PMID36670735
PMCPMC9855194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.