Evidence map›Paper›PMID 36670672›Full record

ArticleChildren (Basel, Switzerland)2023

Importance of Early Intervention in Reducing Autistic Symptoms and Speech-Language Deficits in Children with Autism Spectrum Disorder.

Slavica Maksimović, Maša Marisavljević, Nina Stanojević, Milica Ćirović, Silvana Punišić, Tatjana Adamović, Jelena Đorđević, Ivan Krgović, Miško Subotić

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Artificial Intelligence Methods in Early Detection of Autism Spectrum Disorder: A DSM-5 Criterion-Based Systematic Review.Autism research : official journal of the International Society for Autism Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Slavica MaksimovićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Maša MarisavljevićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Nina StanojevićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Milica ĆirovićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Silvana PunišićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Tatjana AdamovićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
Jelena ĐorđevićClinic for Neurology and Psychiatry for Children and Youth, 11000 Belgrade, Serbia.
Ivan KrgovićInstitute for Children's Diseases, Clinical Center of Montenegro, 81000 Podgorica, Montenegro.
Miško SubotićCognitive Neuroscience Department, Research and Development Institute "Life Activitites Advancement Center", 11000 Belgrade, Serbia.
University of Kragujevac · RSUniversity of Montenegro · ME

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intervention focused on starting treatment at an early age to develop the child’s full potential, which is known as early intervention. Given that autistic symptoms and language deficits occur at an early age and affect other areas of development in children with autistic spectrum disorder, we wanted to examine if early intervention is more effective in the reduction in autistic symptoms and language deficits in children aged 36−47 months old when compared to children 48−60 months old. The sample consisted of 29 children diagnosed with ASD who were admitted for integrative therapy. All participants were divided into two groups based on age: G1: 36−47 months old children, and G2: 48−60 months old children. To estimate the presence of autistic symptoms, we used the GARS-3, and for the assessment of speech−language abilities, we used the subscale Estimated Speech and Language Development (ESLD). Our results regarding the effect of the group on the difference in the scores at two time points showed that there was a statistically significant effect of the group on the reduction in autistic symptoms (p < 0.05) but no effect of the group on the differences in speech−language abilities between the two time points (p > 0.05). Our study highlights the importance of emphasizing the exact age when using the terms “early intervention” and “early development” in future studies and practice because it is necessary to determine and establish guidelines about which particular ages are crucial for starting treatment in certain developmental aspects.

Indexed as

autism spectrum disorderearly interventionindegrative therapy

Identifiers

PMID36670672
PMCPMC9857540
OpenAlexW4313826306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.