ArticleChildren (Basel, Switzerland)2022
Microbiome Changes in Children Treated under General Anesthesia for Severe Early Childhood Caries: Pilot Study.
Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- DNA and RNA-based amplicon sequencing of paired supragingival and dentin lesion plaque in children with severe early childhood caries.International journal of oral science · 2026Article
- Anesthetics change the oral microbial composition of children and increase the abundance of the genusTranslational pediatrics · 2024Article
- A comparative study of microbial changes in dental plaque before and after single- and multiappointment treatments in patients with severe early childhood caries.BMC oral health · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A full-mouth radical dental treatment under general anesthesia is a common approach for treating severe early childhood caries (S-ECC). However, previous study showed recurrence of the disease in 80% of cases within 12 months. The aim of the present study was to examine the changes in microbial composition of the dental biofilm of these children following treatment. Dental biofilm samples from five children (mean age 45.4 ± 10.1 months) were taken before and three months after treatment and analyzed for microbial composition using Next Generation Sequencing of the microbial DNA extracted from these samples. Although some reductions in the abundance of caries-pathogenic bacteria (e.g.,
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