Evidence map›Paper›PMID 36670210›Full record

ArticleAIDS and behavior2023

Optimizing Uptake of Long-Acting Injectable Pre-exposure Prophylaxis for HIV Prevention for Men Who Have Sex with Men.

Lorraine T Dean, Zachary Predmore, Alexandra Skinner, Siena Napoleon, Philip A Chan, Julia Raifman

Abstract read
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorraine T Dean *Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Zachary Predmore *RAND Health Care, RAND Corporation, 20 Park Plaza, Suite 920, Boston, MA, 02116, USA. zpredmor@rand.org.ORCID http://orcid.org/0000-0001-5369-7428
Alexandra SkinnerDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston University, Boston, MA, USA.
Siena NapoleonDepartment of Medicine, Brown University, Providence, RI, USA.
Philip A ChanDepartment of Medicine, Brown University, Providence, RI, USA.
Julia RaifmanDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston University, Boston, MA, USA.

Funding

Predicting the impact of cost on HIV pre-exposure prophylaxis uptake and racial/ethnic disparities among MSMR21MH118019 · NIMH · MIRIAM HOSPITAL · PI CHAN, PHILIP ANDREW, DEAN, LORRAINE TIERA · 2019 to 2020
$452k
NIH HHS 1 R21 MH118019-01NIMH NIH HHS R21 MH118019
6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention tool. Long-acting injectable PrEP (LAI-PrEP) offers another opportunity to reduce HIV. However, how at-risk individuals will consider LAI-PrEP over other modes of administration is unclear. We conducted a discrete choice experiment on preferences for PrEP among a sample of N = 688 gay, bisexual, and other men who have sex with men (GBMSM). We analyzed preferences for mode of administration, side-effects, monetary cost, and time cost using a conditional logit model and predicted preference for PrEP options. LAI-PrEP was preferred, despite mode of administration being the least important PrEP attribute. Side-effects were the most important attribute influencing preferences for PrEP (44% of decision); costs were second-most-important (35% of decision). PrEP with no side-effects was the most important preference, followed by monthly out-of-pocket costs of $0. Practitioners and policymakers looking to increase PrEP uptake should keep costs low, communicate clearly about PrEP side-effects, and allow the use of patient-preferred modes of PrEP administration, including LAI-PrEP.

Indexed as

Anti-HIV AgentsDrug-Related Side Effects and Adverse ReactionsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesHomosexuality, MaleHumansMalePatient Acceptance of Health CareAnti-HIV AgentsHIV preventionImplementationLAI-PrEPMSMPre-exposure prophylaxisPreference elicitation

Identifiers

PMID36670210
PMCPMC9859742

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.