Evidence map›Paper›PMID 36670106›Full record

ArticleScientific data2023

Deep phenotyping and genomic data from a nationally representative study on dementia in India.

Jinkook Lee, Sarah Petrosyan, Pranali Khobragade, Joyita Banerjee, Sandy Chien, Bas Weerman, Alden Gross, Peifeng Hu, Jennifer A Smith, Wei Zhao and 46 more

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Epigenetic aging and blood based neurodegeneration markers in LASI-DAD.The journal of prevention of Alzheimer's disease · 2026
    Article
  3. Article
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  8. Lifespan Normative Modeling of Brain Microstructure.bioRxiv : the preprint server for biology · 2025
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

56 authors at 20 institutions in 4 countries.

Jinkook LeeCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA. jinkookl@usc.edu.
Sarah PetrosyanCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Pranali KhobragadeCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Joyita BanerjeeDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Sandy ChienCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Bas WeermanCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Alden GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Peifeng HuDivision of Geriatric Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Jennifer A SmithDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-3575-5468
Wei ZhaoDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Leon AksmanLaboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA.ORCID http://orcid.org/0000-0003-2342-0780
Urvashi JainDepartment of Economics, Finance and Real Estate, University of South Alabama, Mobile, USA.ORCID http://orcid.org/0000-0002-3455-3346
G S ShanthiDepartment of Geriatric Medicine, Madras Medical College, Chennai, India.
Ravi KurupDepartment of Medicine, Government Medical College, Thiruvananthapuram, India.
Aruna RamanDepartment of Medicine, Government Medical College, Thiruvananthapuram, India.
Sankha Shubhra ChakrabartiDepartment of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Indrajeet Singh GambhirDepartment of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Mathew VargheseDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
John P JohnDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Himanshu JoshiDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Parvaiz A KoulDepartment of Internal and Pulmonary Medicine, Sher-e-Kashmir Institute of Medical Sciences, Srinagar, India.
Debabrata GoswamiDepartment of Medicine, Guwahati Medical College, Guwahati, India.
Arunansu TalukdarDepartment of Geriatric Medicine, Medical College, Kolkata, India.
Rashmi Ranjan MohantyDepartment of Medicine, All India Institute of Medical Sciences, Bhubaneshwar, India.
Y Sathyanarayana Raju YadatiDepartment of Medicine, Nizam's Institute of Medical Sciences, Hyderabad, India.
Mekala PadmajaDepartment of Medicine, Nizam's Institute of Medical Sciences, Hyderabad, India.
Lalit SankheDepartment of Community Medicine, Grant Medical College and J.J. Hospital, Mumbai, India.
Chhaya RajguruDepartment of Community Medicine, Grant Medical College and J.J. Hospital, Mumbai, India.
Monica GuptaDepartment of General Medicine, Government Medical College and Hospital, Chandigarh, India.ORCID http://orcid.org/0000-0002-3992-1013
Govind KumarDepartment of Medicine Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
Minakshi DharDepartment of Medicine, All India Institute of Medical Sciences, Rishikesh, India.
Jorge JovicichCenter for Mind/Brain Sciences, University of Trento, Rovereto, Italy.
Andrea GannaFinnish Institute of Molecular Medicine, University of Helsinki, Helsinki, Finland.
Mary GanguliDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Prasun ChatterjeeDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Sunny SinghalDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Rishav BansalDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Swati BajpaiDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Gaurav DesaiDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Swaroop BhatankarInstitute of Psychological Health, Mumbai, India.
Abhijith R RaoDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
Palanimuthu T SivakumarDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Krishna Prasad MuliyalaDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Preeti SinhaDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Santosh LoganathanDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Erik MeijerCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0001-7959-4670
Marco AngrisaniCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Jung Ki KimSchool of Gerontology, University of Southern California, Los Angeles, CA, USA.
Sharmistha DeyDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Perianayagam ArokiasamyDepartment of Development Studies, International Institute for Population Sciences, Mumbai, India.
David E BloomDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Arthur W TogaLaboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA.
Sharon L R KardiaDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Kenneth LangaDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Eileen M CrimminsSchool of Gerontology, University of Southern California, Los Angeles, CA, USA.
Aparajit B DeyDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
University of Southern California · USAll India Institute of Medical Sciences · INNational Institute of Mental Health and Neurosciences · INUniversity of Michigan · USGovernment Medical College · INGrant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals · INInstitute of Medical Sciences · INNizam's Institute of Medical Sciences · INAll India Institute of Medical Sciences Bhubaneswar · INAll India Institute of Medical Sciences Rishikesh · INGauhati Medical College and Hospital · INGovernment Medical College and Hospital · INHarvard Global Health Institute · USIndira Gandhi Institute of Medical Sciences · INInternational Institute for Population Sciences · INJohns Hopkins University · USKPC Medical College and Hospital · INMadras Medical College · INSher-i-Kashmir Institute of Medical Sciences · INUniversity of California, Los Angeles · US

Funding

Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study of India (LASI)-Genomic study.U01AG064948 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KARDIA, SHARON L, LEE, JINKOOK · 2019 to 2023
$12.5M
Modifiable Protective and Risk Factors of Late-Life Cognitive Health and DementiaRF1AG055273 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LANGA, KENNETH M, LEE, JINKOOK · 2017 to 2017
$4.0M
NIA NIH HHS R01 AG051125NIA NIH HHS RF1 AG055273NIA NIH HHS U01 AG064948
6 · The paper itself

Abstract

The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is a nationally representative in-depth study of cognitive aging and dementia. We present a publicly available dataset of harmonized cognitive measures of 4,096 adults 60 years of age and older in India, collected across 18 states and union territories. Blood samples were obtained to carry out whole blood and serum-based assays. Results are included in a venous blood specimen datafile that can be linked to the Harmonized LASI-DAD dataset. A global screening array of 960 LASI-DAD respondents is also publicly available for download, in addition to neuroimaging data on 137 LASI-DAD participants. Altogether, these datasets provide comprehensive information on older adults in India that allow researchers to further understand risk factors associated with cognitive impairment and dementia.

Indexed as

Cognitive DysfunctionDementiaAgedAgingGenomicsHumansIndiaLongitudinal Studies

Identifiers

PMID36670106
PMCPMC9852797
OpenAlexW4317513358

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.