Evidence map›Paper›PMID 36670017›Full record

ArticleTrends in biochemical sciences2023

In vivo single-molecule RNA structural profiling.

Zhenyin Chen, Hongtao Duan, Xing Li

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in biochemical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zhenyin ChenBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, PR China; University of Chinese Academy of Science, Beijing 100049, PR China.
Hongtao DuanBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, PR China; School of Life Science, Hebei University, Baoding, Hebei 071000, China.
Xing LiBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, PR China; University of Chinese Academy of Science, Beijing 100049, PR China; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: lix@biols.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular RNAs exhibit substantial heterogeneity in structure and function. Recently, Yang et al. developed an in vivo single-molecule RNA structure profiling methodology and revealed that individual isoforms of noncoding transcripts adopt multiple diverse and functionally relevant structural conformations, which change in abundance and structure in response to temperature conditions.

Indexed as

RNARNA, Long NoncodingGene Expression ProfilingRNA, MessengerRNARNA, Long NoncodingRNA, Messengerflowering timein vivolong noncoding RNAssingle-molecule RNAstructural profilingstructure and function

Identifiers

PMID36670017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.