Evidence map›Paper›PMID 36669908›Full record

ArticleAnnals of emergency medicine2023

Robotic Optical Coherence Tomography Retinal Imaging for Emergency Department Patients: A Pilot Study for Emergency Physicians' Diagnostic Performance.

Ailin Song, Kyung-Min Roh, Jay B Lusk, Nita G Valikodath, Eleonora M Lad, Mark Draelos, Pablo Ortiz, Rebecca G Theophanous, Alexander T Limkakeng, Joseph A Izatt and 2 more

Abstract read
In one paragraph

Article in Annals of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Optical coherence tomography in the emergency department setting: a case series.American journal of ophthalmology case reports · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ailin SongDuke University School of Medicine, Durham, NC.
Kyung-Min RohDepartment of Ophthalmology, Duke University, Durham, NC.
Jay B LuskDuke University School of Medicine, Durham, NC.
Nita G ValikodathDepartment of Ophthalmology, Duke University, Durham, NC.
Eleonora M LadDepartment of Ophthalmology, Duke University, Durham, NC.
Mark DraelosDepartment of Biomedical Engineering, Duke University, Durham, NC.
Pablo OrtizDepartment of Biomedical Engineering, Duke University, Durham, NC.
Rebecca G TheophanousDepartment of Emergency Medicine, Duke University, Durham, NC.
Alexander T LimkakengDepartment of Emergency Medicine, Duke University, Durham, NC.
Joseph A IzattDepartment of Biomedical Engineering, Duke University, Durham, NC.
Ryan P McNabbDepartment of Ophthalmology, Duke University, Durham, NC.
Anthony N KuoDepartment of Ophthalmology, Duke University, Durham, NC; Department of Biomedical Engineering, Duke University, Durham, NC. Electronic address: anthony.kuo@duke.edu.

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Portable motion-stabilized optical coherence tomography for eye care in acute care settingsR01EY029302 · NEI · DUKE UNIVERSITY · PI IZATT, JOSEPH A, KUO, ANTHONY NANLIN · 2018 to 2020
$1.1M
NCATS NIH HHS TL1 TR002555NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY029302
6 · The paper itself

Abstract

STUDY

objectiveTo evaluate the diagnostic performance of emergency physicians' interpretation of robotically acquired retinal optical coherence tomography images for detecting posterior eye abnormalities in patients seen in the emergency department (ED).

methodsAdult patients presenting to Duke University Hospital emergency department from November 2020 through October 2021 with acute visual changes, headache, or focal neurologic deficit(s) who received an ophthalmology consultation were enrolled in this pilot study. Emergency physicians provided standard clinical care, including direct ophthalmoscopy, at their discretion. Retinal optical coherence tomography images of these patients were obtained with a robotic, semi-autonomous optical coherence tomography system. We compared the detection of abnormalities in optical coherence tomography images by emergency physicians with a reference standard, a combination of ophthalmology consultation diagnosis and retina specialist optical coherence tomography review.

resultsNine emergency physicians reviewed the optical coherence tomography images of 72 eyes from 38 patients. Based on the reference standard, 33 (46%) eyes were normal, 16 (22%) had at least 1 urgent/emergency abnormality, and the remaining 23 (32%) had at least 1 nonurgent abnormality. Emergency physicians' optical coherence tomography interpretation had 69% (95% confidence interval [CI], 49% to 89%) sensitivity for any abnormality, 100% (95% CI, 79% to 100%) sensitivity for urgent/emergency abnormalities, 48% (95% CI, 28% to 68%) sensitivity for nonurgent abnormalities, and 64% (95% CI, 44% to 84%) overall specificity. In contrast, emergency physicians providing standard clinical care did not detect any abnormality with direct ophthalmoscopy.

conclusionRobotic, semi-autonomous optical coherence tomography enabled ocular imaging of emergency department patients with a broad range of posterior eye abnormalities. In addition, emergency provider optical coherence tomography interpretation was more sensitive than direct ophthalmoscopy for any abnormalities, urgent/emergency abnormalities, and nonurgent abnormalities in this pilot study with a small sample of patients and emergency physicians.

Indexed as

Eye AbnormalitiesPhysiciansRobotic Surgical ProceduresAdultEmergency Service, HospitalHumansPilot ProjectsRetinaTomography, Optical Coherence

Identifiers

PMID36669908
PMCPMC10038849

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.