Evidence map›Paper›PMID 36669899›Full record

ArticleJACC. Clinical electrophysiology2023

Electrogram Morphology Recurrence for Mapping Persistent Atrial Fibrillation: Initial vs Redo Catheter Ablation.

Ghaith Zaatari, Raul Mitrani, Jorge Bohorquez, Jason Ng, Justin Ng, Harold Rivner, Alex Velasquez, Litsa Lambrakos, Rishi Arora, Jeffrey J Goldberger

Abstract read
In one paragraph

Article in JACC. Clinical electrophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Electrogram morphology recurrence guided catheter ablation for repeat ablation of persistent atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  5. Comparison of electrogram characteristics in persistent atrial fibrillation.Journal of cardiovascular electrophysiology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Ghaith ZaatariDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA.
Raul MitraniDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA.
Jorge BohorquezDepartment of Biomedical Engineering, University of Miami, Miami, Florida, USA.
Jason NgUniversity of Illinois, College of Medicine, Chicago, Illinois, USA.
Justin NgNorthwestern University, Chicago, Illinois, USA.
Harold RivnerDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA.
Alex VelasquezDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA.
Litsa LambrakosDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA.
Rishi AroraNorthwestern University, Chicago, Illinois, USA.
Jeffrey J GoldbergerDivision of Cardiology, Department of Medicine, University of Miami, Miami, Florida, USA. Electronic address: j-goldberger@miami.edu.

Funding

New and Disruptive Therapeutic Approaches to Target Fundamental Molecular Mechanisms Underlying Atrial FibrillationR35HL161249 · NHLBI · UNIVERSITY OF CHICAGO · PI Rishi Arora · 2022 to 2026
$5.1M
The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heartR01HL152712 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI, ZHAO, MING · 2021 to 2024
$3.0M
Pathophysiological Significance of Atrial Fibrillation Electrogram PatternsR01HL125881 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2015 to 2019
$2.4M
Oxidative stress contributes to atrial fibrillation by causing remodeling of the autonomic nervous systemR01HL140061 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARORA, RISHI · 2018 to 2021
$2.3M
Mapping electrogram morphology recurrence for atrial fibrillation ablationR41HL127907 · NHLBI · GOLD T-TECH, INC. · PI NG, JASON · 2015 to 2015
$225k
NHLBI NIH HHS R01 HL125881NHLBI NIH HHS R01 HL140061NHLBI NIH HHS R01 HL152712NHLBI NIH HHS R35 HL161249NHLBI NIH HHS R41 HL127907
6 · The paper itself

Abstract

backgroundElectrogram (EGM) morphology recurrence (EMR) mapping of persistent atrial fibrillation (AF) quantifies consistency of activation and is expected to be high and rapid near AF drivers.

objectivesThe purpose of this study was to compare EMR in left atria (LA) and right atria (RA) in patients undergoing first vs redo ablation for persistent AF.

methodsMultisite LA/RA mapping (LA: 281 ± 176 sites/patient; RA: 239 ± 166 sites/patient) before persistent AF ablation was performed in 42 patients (30 males, age 63 ± 9 years) undergoing first (Group 1, n = 32) or redo ablation (Group 2, n = 10). After cross-correlation of each automatically detected EGM with every other EGM per recording, the most recurrent electrogram morphology was identified and its frequency (Rec%) and recurrence cycle length (CL

resultsIn Groups 1 and 2, minimum CL

conclusionsEMR identified the shortest CL

Indexed as

Atrial AppendageAtrial FibrillationCatheter AblationAgedElectrophysiologic Techniques, CardiacHeart AtriaHumansMaleMiddle Agedablationatrial fibrillationelectrogramelectrogram morphology recurrencemapping

Identifiers

PMID36669899
PMCPMC10699542

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.