Evidence map›Paper›PMID 36669847›Full record

ArticleBMJ open2023

PREP Plus combined postrehabilitation programme to support upper limb recovery in community-dwelling stroke survivors: protocol for a mixed-methods, cluster-assigned feasibility study.

Katy Pedlow, Suzanne McDonough, Natalie Klempel, Jenny Hylands, Noelene Hughes, Zoe Campbell, Janice J Eng, Aoife Stephenson, Niamh Kennedy

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05090163 (Prep Plus), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05090163 nacompletednot on this map

Prep Plus: Supporting Upper Limb Practice in Community Dwelling Stroke Survivors

TypeinterventionalSponsorUniversity of UlsterRan2022 to 2023Enrolled74ConditionsStrokeArmsPREP Plus, PREP
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katy PedlowSchool of Health Sciences, Ulster University, Londonderry, UK K.Pedlow@ulster.ac.uk.
Suzanne McDonoughPhysiotherapy, RCSI, Dublin, Ireland.ORCID 0000-0003-3758-3302
Natalie KlempelSchool of Health Sciences, Ulster University, Londonderry, UK.ORCID 0000-0001-7937-6470
Jenny HylandsSchool of Health Sciences, Ulster University, Londonderry, UK.
Noelene HughesNorthern Ireland Chest Heart and Stroke, Belfast, UK.
Zoe CampbellNorthern Ireland Chest Heart and Stroke, Belfast, UK.
Janice J EngPhysical Therapy, University of British Columbia, Vancouver, Columbia, Canada.
Aoife StephensonPhysiotherapy, RCSI, Dublin, Ireland.
Niamh KennedySchool of Psychology, Ulster University, Coleraine, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPoor recovery of the upper limb following a stroke has been recognised as a significant problem in the UK. Although there is good evidence that early, intense rehabilitation can lead to upper limb recovery, often this is not maintained, with less than 50% of people regaining the ability to use their upper limb for independent function at 6 months. Upper limb recovery potential is reported for many years poststroke, yet current long-term provision is insufficient. METHODS AND ANALYSIS: 60 participants will be recruited into this feasibility study, with 30 allocated to a Post Rehabilitation Enablement Programme (PREP) alone and 30 allocated to a combined programme, PREP Plus, consisting of PREP and the Graded Repetitive Arm Supplementary Programme (GRASP). We will aim to complete four iterative waves. Within each wave, the intervention design will be refined, based on participant feedback. Within each wave, there will be one cluster unit (one intervention group ;PREP Plus) and one control group ;PREP alone)). A total of five PREP sites within Northern Ireland Health and Social Care Trusts will be used for this study. PREP Plus will have a home exercise component along with exercises logs and a behaviour contract. Qualitative and quantitative measures will evaluate the acceptability and feasibility to determine how feasible it is to embed the intervention into practice, as well as to determine the feasibility of a larger, mixed-methods, randomised controlled trial to assess intervention efficacy. Clinical endpoints will also be explored. ETHICS AND DISSEMINATION: This study has been approved by the Health and Social Care Research Ethics Committee A, IRAS project ID (278620). Participants will provide informed consent prior to participating in the study. Information outlining the purpose of the study, what data will be collected and how the data will be managed will be provided. Results will be published in peer-reviewed journals and any published data will be available on the university data repository. The project management group will advise on different avenues for dissemination to ensure it reaches appropriate audiences. TRIAL REGISTRATION NUMBER: NCT05090163.

Indexed as

StrokeStroke RehabilitationFeasibility StudiesHumansIndependent LivingQuality of LifeRandomized Controlled Trials as TopicSurvivorsUpper ExtremityREHABILITATION MEDICINEStrokeSTROKE MEDICINE

Identifiers

PMID36669847
PMCPMC9872469

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.