Evidence map›Paper›PMID 36669747›Full record

ArticleNeuroImage2023

LARO: Learned acquisition and reconstruction optimization to accelerate quantitative susceptibility mapping.

Jinwei Zhang, Pascal Spincemaille, Hang Zhang, Thanh D Nguyen, Chao Li, Jiahao Li, Ilhami Kovanlikaya, Mert R Sabuncu, Yi Wang

Abstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jinwei ZhangDepartment of Biomedical Engineering, Cornell University, Ithaca, NY, USA; Department of Radiology, Weill Medical College of Cornell University, New York, NY, USA.
Pascal SpincemailleDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA.
Hang ZhangDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA; Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, USA.
Thanh D NguyenDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA.
Chao LiDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA; Department of Applied Physics, Cornell University, Ithaca, NY, USA.
Jiahao LiDepartment of Biomedical Engineering, Cornell University, Ithaca, NY, USA; Department of Radiology, Weill Medical College of Cornell University, New York, NY, USA.
Ilhami KovanlikayaDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA.
Mert R SabuncuDepartment of Radiology, Weill Medical College of Cornell University, New York, NY, USA; Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, USA.
Yi WangDepartment of Biomedical Engineering, Cornell University, Ithaca, NY, USA; Department of Radiology, Weill Medical College of Cornell University, New York, NY, USA. Electronic address: yiwang@med.cornell.edu.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
No-Gd MRI for Monitoring Disease Status in Multiple SclerosisR01NS105144 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAUTHIER, SUSAN A, GUPTA, AJAY · 2018 to 2022
$2.8M
Advanced machine learning algorithms that integrate genomewide, longitudinal MRI and demographic data to predict future cognitive decline toward dementiaR01AG053949 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI SABUNCU, MERT RORY · 2017 to 2021
$2.4M
Multiple Sclerosis Lesion Magnetic Susceptibility ActivityR01NS090464 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI WANG, YI · 2015 to 2020
$2.3M
3.0T Magnetic Resonance Imaging System for Preclinical, Translational and Clinical ResearchS10OD021782 · OD · WEILL MEDICAL COLL OF CORNELL UNIV · PI WANG, YI · 2016 to 2016
$2.0M
Novel Bioinformatics Strategies to Study Associations Between Genetic Variants and Neuroanatomical ShapeR01LM012719 · NLM · CORNELL UNIVERSITY · PI SABUNCU, MERT RORY · 2017 to 2020
$1.4M
Quantitative susceptibility mapping of carotid intraplaque hemorrhageR21NS116516 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, NGUYEN, THANH D · 2020 to 2021
$466k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NIA NIH HHS R01 AG053949NIH HHS S10 OD021782NINDS NIH HHS R01 NS090464NINDS NIH HHS R01 NS105144NINDS NIH HHS R21 NS116516NLM NIH HHS R01 LM012719
6 · The paper itself

Abstract

Quantitative susceptibility mapping (QSM) involves acquisition and reconstruction of a series of images at multi-echo time points to estimate tissue field, which prolongs scan time and requires specific reconstruction technique. In this paper, we present our new framework, called Learned Acquisition and Reconstruction Optimization (LARO), which aims to accelerate the multi-echo gradient echo (mGRE) pulse sequence for QSM. Our approach involves optimizing a Cartesian multi-echo k-space sampling pattern with a deep reconstruction network. Next, this optimized sampling pattern was implemented in an mGRE sequence using Cartesian fan-beam k-space segmenting and ordering for prospective scans. Furthermore, we propose to insert a recurrent temporal feature fusion module into the reconstruction network to capture signal redundancies along echo time. Our ablation studies show that both the optimized sampling pattern and proposed reconstruction strategy help improve the quality of the multi-echo image reconstructions. Generalization experiments show that LARO is robust on the test data with new pathologies and different sequence parameters. Our code is available at https://github.com/Jinwei1209/LARO-QSM.git.

Indexed as

BrainMagnetic Resonance ImagingHumansImage Processing, Computer-AssistedProspective StudiesMulti-echo gradient echoQuantitative susceptibility mappingSampling pattern optimizationUnrolled reconstruction

Identifiers

PMID36669747
PMCPMC10021353

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.