Evidence map›Paper›PMID 36669112›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen

Asiya Gusa, Vikas Yadav, Cullen Roth, Jonathan D Williams, Eva Mei Shouse, Paul Magwene, Joseph Heitman, Sue Jinks-Robertson

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Thermal adaptation crosstalk with azole response through lncRNA inbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Asiya GusaDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.ORCID 0000-0001-9915-1834
Vikas YadavDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.ORCID 0000-0003-2650-9035
Cullen RothDepartment of Biology, Duke University, Durham, NC 27710.
Jonathan D WilliamsDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.
Eva Mei ShouseDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.
Paul MagweneDepartment of Biology, Duke University, Durham, NC 27710.ORCID 0000-0002-7659-2589
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.ORCID 0000-0001-6369-5995
Sue Jinks-RobertsonDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710.ORCID 0000-0001-5924-5852
Duke University · US

Funding

Tri-Institutional Molecular Mycology and Pathogenesis Training ProgramT32AI052080 · NIAID · DUKE UNIVERSITY · PI ANDREW ALSPAUGH, JOSEPH HEITMAN · 2003 to 2026
$8.7M
Structure, function, and evolution of the Cryptococcus MAT locusR01AI050113 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2002 to 2024
$8.5M
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITINGR01AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 1997 to 2025
$6.7M
Genetics of Cryptococcus sexual reproductionR37AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2011 to 2020
$4.9M
The Genetic Basis of Virulence in Cryptococcus NeoformansR01AI133654 · NIAID · DUKE UNIVERSITY · PI JOSEPH HEITMAN, Paul Mitaari Magwene · 2017 to 2026
$4.7M
Regulation of mitotic genome stability in yeast.R35GM118077 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 2016 to 2023
$4.5M
Temperature-dependent transposon mobilization in Cryptococcus neoformansR21AI133644 · NIAID · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 2017 to 2018
$437k
Stress-induced transposon mobilization in the human fungal pathogen CryptococcusK99AI166094 · NIAID · DUKE UNIVERSITY · PI GUSA, ASIYA · 2022 to 2023
$197k
NIAID NIH HHS K99 AI166094NIAID NIH HHS R01 AI039115NIAID NIH HHS R01 AI050113NIAID NIH HHS R01 AI133654NIAID NIH HHS R21 AI133644NIAID NIH HHS R37 AI039115NIAID NIH HHS T32 AI052080NIGMS NIH HHS R35 GM118077
6 · The paper itself

Abstract

We recently reported transposon mutagenesis as a significant driver of spontaneous mutations in the human fungal pathogen

Indexed as

CryptococcosisCryptococcus neoformansAnimalsDNA Transposable ElementsGenomeHeat-Shock ResponseHumansMiceRetroelementsDNA Transposable ElementsRetroelementsCryptococcusfungal pathogenheat stresstemperaturetransposons

Identifiers

PMID36669112
PMCPMC9942834
OpenAlexW4317566711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.