Evidence map›Paper›PMID 36668928›Full record

ArticleTropical medicine and infectious disease2022

No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda.

Arthur W D Edridge, Nathalie van den Brekel, Philly Mukungu, Rachael Nakayima, Samuel Bbosa, Peter Isagara, Michael van Boele Hensbroek, Lia van der Hoek, John Kayiwa, Julius J Lutwama and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Arthur W D EdridgeCenter for Global Child Health, Emma's Children Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-9264-5874
Nathalie van den BrekelCenter for Global Child Health, Emma's Children Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Philly MukunguKiboga District Hospital, Kiboga P.O. Box 17, Uganda.
Rachael NakayimaKiboga District Hospital, Kiboga P.O. Box 17, Uganda.
Samuel BbosaKiboga District Hospital, Kiboga P.O. Box 17, Uganda.
Peter IsagaraKiboga District Hospital, Kiboga P.O. Box 17, Uganda.
Michael van Boele HensbroekCenter for Global Child Health, Emma's Children Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Lia van der HoekVirus Discovery Group, Laboratory of Experimental Virology, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-2803-642X
John KayiwaDepartment of Arbovirology, Ugandan Virus Research Institute, Entebbe P.O. Box 49, Uganda.ORCID 0000-0002-1840-1801
Julius J LutwamaDepartment of Arbovirology, Ugandan Virus Research Institute, Entebbe P.O. Box 49, Uganda.
Richard IdroDepartment of Paediatrics, Mulago Hospital, College of Health Science, Makerere University, Kampala P.O. Box 7051, Uganda.ORCID 0000-0003-4728-4605
Amsterdam University Medical Centers · NLUganda Virus Research Institute · UGMulago Hospital · UG

Funding

European Society of Clinical Microbiology and Infectious Diseases Research grantPrimaGen Holding Research grantSchumacher Kramer Foundation Research grant
6 · The paper itself

Abstract

We investigated whether Ntwetwe virus-a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy-was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case-control was conducted between September 2019 and September 2020, including cases with severe neurological disease and mild febrile illness, matched to a healthy control without fever. Among 143 subjects, no cases with an acute infection were identified. This result suggests that Ntwetwe virus does not cause a major burden of disease amongst children presenting to Kiboga hospital during the study period.

Indexed as

CNS infectionemerging infectious diseasesorthobunyaviruspediatricsUgandavirus discovery

Identifiers

PMID36668928
PMCPMC9865167
OpenAlexW4313260280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.