Evidence map›Paper›PMID 36668925›Full record

ArticleTropical medicine and infectious disease2022

Characterization of Regulatory T Cells in Patients Infected by

Rephany F Peixoto, Bruna M Gois, Marineuma Martins, Pedro Henrique S Palmeira, Juliana C Rocha, Juliana A S Gomes, Fátima L A A Azevedo, Robson C Veras, Isac A de Medeiros, Teresa C S L Grisi and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rephany F PeixotoImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-1060-4740
Bruna M GoisImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Marineuma MartinsImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Pedro Henrique S PalmeiraImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.ORCID 0000-0002-9323-7677
Juliana C RochaImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Juliana A S GomesDepartment of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Pampulha, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-8332-2907
Fátima L A A AzevedoResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
Robson C VerasResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0002-2083-6898
Isac A de MedeirosResearch Institute for Drugs and Medicines, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
Teresa C S L GrisiDepartment of Biotechnology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Demétrius A M de AraújoDepartment of Biotechnology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Ian P G AmaralImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-1923-6219
Tatjana S L KeesenImmunology of Infectious Diseases Laboratory, Department of Cellular and Molecular Biology, Federal University of Paraiba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-0964-389X
Universidade Federal da Paraíba · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High IL-10 levels are pivotal to parasite survival in visceral leishmaniasis (VL). Antigenic stimuli induce IL-10 expression and release of adenosine by CD39/CD73. Due their intrinsic ability to express IL-10 and produce adenosine from extracellular ATP, we evaluated the IL-10, CD39, and CD73 expression by Regulatory T cells (Treg) correlated with VL pathology. Using flow cytometry, Treg cells was analyzed in peripheral blood samples from VL patients (in the presence and absence of

Indexed as

human leishmaniasisregulatory T cellsVL immunomodulation

Identifiers

PMID36668925
PMCPMC9864225
OpenAlexW4313260014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.