Evidence map›Paper›PMID 36668784›Full record

ArticleToxics2023

Exposure Characteristics and Cumulative Risk Assessment for Phthalates in Children Living near a Petrochemical Complex.

Chih-Wen Wang, Po-Keng Cheng, Vinoth Kumar Ponnusamy, Hung-Che Chiang, Wan-Ting Chang, Po-Chin Huang

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Identification of chemicals targeting dementia genes and pathways in the Comparative Toxicogenomics Database.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Chih-Wen WangDivision of Hepatobiliary, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 701, Taiwan.
Po-Keng ChengDepartment of Finance and Cooperative Management, National Taipei University, New Taipei City 237, Taiwan.
Vinoth Kumar PonnusamyResearch Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung 701, Taiwan.ORCID 0000-0003-2112-2085
Hung-Che ChiangDepartment of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan.
Wan-Ting ChangNational Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli 350, Taiwan.
Po-Chin HuangResearch Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung 701, Taiwan.ORCID 0000-0002-9243-0838
Kaohsiung Medical University · TWChina Medical University · TWNational Health Research Institutes · TWNational Taipei University · TW

Funding

Kaohsiung Medical University KMHK-H-110-009Kaohsiung Medical University KMHK-S-110-004National Health Research Institutes EM-111-SP03National Health Research Institutes NHRIKMU-111-I004-1
6 · The paper itself

Abstract

backgroundSchool-aged children living near plastics-producing factories may have higher risk of exposure to phthalates released during the manufacturing processes.

objectivesWe aimed to investigate the urinary concentrations of phthalate metabolites in school-aged children living near a petrochemical complex and estimate the cumulative risk of phthalate exposure.

methodsWe used a well-established cohort (Taiwan Petrochemical Complex Cohort for Children, TPE3C) of school-aged children (6-13 years old) living near polyvinyl chloride (PVC) and vinyl chloride monomer (VCM) factories in central Taiwan from October 2013 to September 2014. A total of 257 children were included from five elementary schools: Syu-Cuo Branch (

resultsThe geometric mean and proportion of participants with HIs exceeding one for hepatic (HI

conclusionsOur findings suggest that children living near a petrochemical complex were at a greater risk of phthalate exposure than normal school-aged children and that phthalate exposure was mainly attributed to DEHP, DiBP and DnBP. In addition, inhalation may have been a risk factor for people living near to PVC and VCM factories.

Indexed as

daily intakeshazard indexhazard quotientpetrochemical complexphthalate metabolites

Identifiers

PMID36668784
PMCPMC9865072
OpenAlexW4313828971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.