Evidence map›Paper›PMID 36662868›Full record

ArticleScience advances2023

Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling.

Si Chen, Fangyuan Shao, Jianming Zeng, Sen Guo, Lijian Wang, Heng Sun, Josh Haipeng Lei, Xueying Lyu, Shuai Gao, Qiang Chen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Ubiquitination in cancer: mechanisms and therapeutic opportunities.Cancer communications (London, England) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Si ChenCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0003-0557-046X
Fangyuan ShaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0001-9999-4276
Jianming ZengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0003-4835-6009
Sen GuoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0002-2681-0576
Lijian WangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0002-2726-9654
Heng SunCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Josh Haipeng LeiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0002-2058-8054
Xueying LyuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0002-2885-3940
Shuai GaoKey Laboratory of Animal Genetics, Breeding and Reproduction of the MARA, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China.ORCID 0000-0002-8208-9197
Qiang ChenCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Kai MiaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0003-4832-3354
Xiaoling XuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Chu-Xia DengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.ORCID 0000-0001-8033-3902
University of Macau · MOChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer-associated gene 1 (

Indexed as

Cullin ProteinsMammary Neoplasms, AnimalAnimalsCyclic AMP Response Element-Binding ProteinGenes, Tumor SuppressorMiceSignal TransductionTumor MicroenvironmentCullin ProteinsCyclic AMP Response Element-Binding Protein

Identifiers

PMID36662868
PMCPMC9858512
OpenAlexW4317601318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.