Evidence map›Paper›PMID 36662865›Full record

ArticleScience advances2023

The HIPK2/CDC14B-MeCP2 axis enhances the spindle assembly checkpoint block by promoting cyclin B translation.

Patrick Partscht, Alexander Simon, Nan-Peng Chen, Sylvia Erhardt, Elmar Schiebel

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. When the Clock Is Ticking: The Role of Mitotic Duration in Cell Fate Determination.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
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  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patrick PartschtZentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany.ORCID 0000-0002-8766-3901
Alexander SimonHeidelberg Biosciences International Graduate School (HBIGS), Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0003-3067-5028
Nan-Peng ChenZentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany.ORCID 0000-0001-8061-9732
Sylvia ErhardtZoological Institute, Karlsruhe Institute of Technology (KIT), Karlsruhe 76131, Germany.ORCID 0000-0003-3169-241X
Elmar SchiebelZentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany.ORCID 0000-0002-3683-247X
Heidelberg University · DEKarlsruhe Institute of Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitotic perturbations activate the spindle assembly checkpoint (SAC) that keeps cells in prometaphase with high CDK1 activity. Prolonged mitotic arrest is eventually bypassed by gradual cyclin B decline followed by slippage of cells into G

Indexed as

MitosisM Phase Cell Cycle CheckpointsCarrier ProteinsCell Cycle CheckpointsCyclin B1Dual-Specificity PhosphatasesMethyl-CpG-Binding Protein 2PhosphorylationProtein Serine-Threonine KinasesCarrier ProteinsCyclin B1Dual-Specificity PhosphatasesMethyl-CpG-Binding Protein 2Protein Serine-Threonine Kinases

Identifiers

PMID36662865
PMCPMC9858502
OpenAlexW4317556164

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.