Evidence map›Paper›PMID 36662764›Full record

ArticlePloS one2023

Behavioural activation for depressive symptoms in young people with emerging or early psychosis: A pilot study protocol.

Mitchell K Byrne, Bróna Nic Giolla Easpaig, Richard Gray, Rebecca Creek, Martin Jones, Ellie Brown, David Mitchell, Jianxia Zhai, Jing-Yu Tan, Shaun Denis and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mitchell K ByrneCollege of Health and Human Sciences, Charles Darwin University, Darwin, Northern Territory, Australia.ORCID 0000-0003-0823-2917
Bróna Nic Giolla EaspaigCollege of Nursing and Midwifery, Charles Darwin University, Darwin, Northern Territory, Australia.ORCID 0000-0001-6787-056X
Richard GraySchool of Nursing and Midwifery, La Trobe University, Bundoora, Victoria, Australia.
Rebecca CreekHeadspace Darwin, Casuarina, Northern Territory, Australia.
Martin JonesDepartment of Rural Health, University of South Australia, Whyalla, Australia.
Ellie BrownCentre for Youth Mental Health, Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.
David MitchellNorthern Territory Top End Health Service, Casuarina, Northern Territory, Australia.
Jianxia ZhaiCollege of Nursing and Midwifery, Charles Darwin University, Darwin, Northern Territory, Australia.
Jing-Yu TanCollege of Nursing and Midwifery, Charles Darwin University, Darwin, Northern Territory, Australia.
Shaun DenisWhyalla Health Services, Whyalla, South Australia, Australia.ORCID 0000-0002-1469-6083
Daniel BressingtonCollege of Nursing and Midwifery, Charles Darwin University, Darwin, Northern Territory, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTheoretically, behavioural activation may have a valuable role to play in the treatment of depression among young people with emerging/early psychosis, however we lack trial evidence concerning its acceptability and feasibility. This study will establish the feasibility of clinician-delivered behavioural activation as an adjunct to standard care for this population. We aim to train and support clinicians in delivering behavioural activation to improve depressive symptoms in young people with early/emerging psychosis. Our objectives are to: Establish the number of young people with early/emerging psychosis with clinically meaningful depression symptoms.Establish the proportion of clinicians that complete the behavioural activation training and are deemed to be competent.Determine the proportion of eligible participants approached who agree to consent to the research.Determine the proportion of participants that complete baseline measures, complete behavioural activation treatment (attending for at least fifteen minutes in a minimum of eight sessions), and complete follow-up measures (immediately post-intervention and at 3 months follow-up).Establish clinicians' fidelity to treatment (by recording randomly selected treatment sessions and completing a fidelity checklist).Calculate preliminary efficacy of behavioural activation against primary and secondary outcomes.Explore participants' experiences of facilitating behavioural activation (clinicians) and receiving behavioural activation (young people with emerging/early psychosis).

methodThis is a pilot controlled clinical trial with a two-arm parallel-group study. Approximately 60 young people with emerging/early psychosis will be randomly allocated to either behavioural activation treatment plus standard care or standard care alone. The primary outcome: depressive symptoms; and secondary outcomes: negative symptoms, overall psychiatric symptoms, medication side effects and functioning, will be assessed at baseline, post-intervention and at 3-months follow-up. The protocol is registered with the Australian New Zealand Clinical Trials Registry (reference number: ACTRN12622000756729). DISCUSSION: The findings will inform the design of a full-scale randomised controlled trial.

Indexed as

Cognitive Behavioral TherapyPsychotic DisordersAdolescentAustraliaDepressionHumansPilot ProjectsRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

PMID36662764
PMCPMC9858082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.