ArticlePloS one2023
Occurrence, fate, and risk assessment of antibiotics in typical pharmaceutical manufactories and receiving water bodies from different regions.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 53 citations in OpenAlex.
- Nanoparticles for targeted removal of emerging contaminants in wastewater: mechanisms and sustainable practices.Discover nano · 2025Review
- Micropollutants and Their Interactions With Relevant Environmental Viruses.Environmental microbiology · 2025Review
- Sustainable adsorbent design: ZnSA@PEG from agricultural waste for environmental remediation.World journal of microbiology & biotechnology · 2025Article
- Supradecoration induced homogenous electrochemical sensing: development of Ru(ii) half sandwich complex as isoniazid and rifampicin dual sensor.RSC advances · 2025Article
- Antibiotic Concentrations in Aquatic Environments of the African Continent: A Systematic Review and Predicted No-Effect Concentration (PNEC) Assessment.Environmental health insights · 2025Review
- Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review.Environmental health insights · 2025Review
- Aero-TiOScientific reports · 2024Article
- A Review on Fluoroquinolones' Toxicity to Freshwater Organisms and a Risk Assessment.Journal of xenobiotics · 2024Review
- Pharmaceutically active micropollutants: origin, hazards and removal.Frontiers in microbiology · 2024Review
- Impact of veterinary pharmaceuticals on environment and their mitigation through microbial bioremediation.Frontiers in microbiology · 2024Review
- Occurrence, Bioaccumulation, Metabolism and Ecotoxicity of Fluoroquinolones in the Aquatic Environment: A Review.Toxics · 2023Review
- Fabrication of new composite NCuTiOScientific reports · 2023Article
- Spatial Distribution and Risk Assessment of Antibiotics in 15 Pharmaceutical Plants in the Pearl River Delta.Toxics · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the presence and persistence of antibiotics in wastewater of four typical pharmaceutical manufactories in China and receiving water bodies and suggest the removal of antibiotics by the wastewater treatment process. It also evaluated the environmental impact of antibiotic residues through wastewater discharge into receiving water bodies. The results indicated that thirteen antibiotics were detected in wastewater samples with concentrations ranging from 57.03 to 726.79 ng/L. Fluoroquinolones and macrolides were the most abundant antibiotic classes found in wastewater samples, accounting for 42.5% and 38.7% of total antibiotic concentrations, respectively, followed by sulfonamides (16.4%) and tetracyclines (2.4%). Erythromycin-H2O, lincomycin, ofloxacin, and trimethoprim were the most frequently detected antibiotics; among these antibiotics, the concentration of ofloxacin was the highest in most wastewater samples. No significant difference was found in different treatment processes used to remove antibiotics in wastewater samples. More than 50% of antibiotics were not completely removed with a removal efficiency of less than 70%. The concentration of detected antibiotics in the receiving water bodies was an order of magnitude lower than that in the wastewater sample due to dilution. An environmental risk assessment showed that lincomycin and ofloxacin could pose a high risk at the concentrations detected in effluents and a medium risk in their receiving water bodies, highlighting a potential hazard to the health of the aquatic ecosystem. Overall, The investigation was aimed to determine and monitor the concentration of selected antibiotics in 4 typical PMFs and their receiving water bodies, and to study the removal of these substances in PMFs. This study will provide significant data and findings for future studies on antibiotics-related pollution control and management in water bodies.
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