Evidence map›Paper›PMID 36662637›Full record

ReviewChemical reviews2023

A New Phase of Networking: The Molecular Composition and Regulatory Dynamics of Mammalian Stress Granules.

Sean R Millar, Jie Qi Huang, Karl J Schreiber, Yi-Cheng Tsai, Jiyun Won, Jianping Zhang, Alan M Moses, Ji-Young Youn

Open access · bronzeAbstract readReview
In one paragraph

Review in Chemical reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 110 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Prion-Like Protein LENG8-Mediated Nucleation Drives Stress Granule Assembly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Ferroptosis Suppression by the MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. TDP-43 Aggregation: The Healthy-Toxic Balance of the Prion-Like Domain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. TSC2 is a stress granule suppressor.bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Generative design of intrinsically disordered protein regions with IDiom.bioRxiv : the preprint server for biology · 2026
    Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sean R MillarDepartment of Molecular Genetics, University of Toronto, Toronto, OntarioM5S 1A8, Canada.
Jie Qi HuangDepartment of Molecular Genetics, University of Toronto, Toronto, OntarioM5S 1A8, Canada.
Karl J SchreiberProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, OntarioM5G 0A4, Canada.
Yi-Cheng TsaiDepartment of Molecular Genetics, University of Toronto, Toronto, OntarioM5S 1A8, Canada.
Jiyun WonDepartment of Cell & Systems Biology, University of Toronto, Toronto, OntarioM5S 3B2, Canada.
Jianping ZhangLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, OntarioM5G 1X5, Canada.
Alan M MosesDepartment of Cell & Systems Biology, University of Toronto, Toronto, OntarioM5S 3B2, Canada.
Ji-Young YounDepartment of Molecular Genetics, University of Toronto, Toronto, OntarioM5S 1A8, Canada.ORCID 0000-0001-6799-5709
University of Toronto · CAHospital for Sick Children · CALunenfeld-Tanenbaum Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress granules (SGs) are cytosolic biomolecular condensates that form in response to cellular stress. Weak, multivalent interactions between their protein and RNA constituents drive their rapid, dynamic assembly through phase separation coupled to percolation. Though a consensus model of SG function has yet to be determined, their perceived implication in cytoprotective processes (

Indexed as

Amyotrophic Lateral SclerosisProteomeHumansProteomicsRNAStress GranulesProteomeRNA

Identifiers

PMID36662637
PMCPMC10375481
OpenAlexW4317549025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.