Evidence map›Paper›PMID 36662632›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the

Lali M Al-Harbi, Eman A Al-Harbi, Rawda M Okasha, R A El-Eisawy, Mohammed A A El-Nassag, Hany M Mohamed, Ahmed M Fouda, Ahmed A Elhenawy, Ahmed Mora, Ahmed M El-Agrody and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Benzo[ACS omega · 2026
    Article
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  7. New cyclic glycolipids fromRSC advances · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Lali M Al-HarbiChemistry Department, Faculty of Science, King Abdul-AzizUniversity, Jeddah, Saudi Arabia.
Eman A Al-HarbiChemistry Department, Faculty of Science, Taibah University, Medina, Saudi Arabia.
Rawda M OkashaChemistry Department, Faculty of Science, Taibah University, Medina, Saudi Arabia.ORCID 0000-0001-9453-8132
R A El-EisawyChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Mohammed A A El-NassagChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Hany M MohamedChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Ahmed M FoudaChemistry Department, Faculty of Science, King Khalid University, Abha, Saudi Arabia.
Ahmed A ElhenawyChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.ORCID 0000-0003-2893-0376
Ahmed MoraChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Ahmed M El-AgrodyChemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.ORCID 0000-0001-7019-411X
Heba K A El-MawgoudChemistry Department, Faculty of Women for Arts, Science, and Education, Ain Shams University, Cairo, Egypt.
Al-Azhar University · EGTaibah University · SAAin Shams University · EGKing Abdul Aziz University Hospital · SAKing Khalid University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 1

Indexed as

Antineoplastic AgentsNeoplasmsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1BenzopyransDoxorubicinDrug Resistance, NeoplasmHumansMCF-7 CellsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1BenzopyransDoxorubicin1H-Benzo[f]chromenesantitumor activitycell cycle arrestMCF-7/ADRP-glycoproteinSARUltrasound synthesiswestern blot

Identifiers

PMID36662632
PMCPMC9869995
OpenAlexW4317548424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.