ArticleInvestigative ophthalmology & visual science2023
Relationship Between Scleral Thickness and Choroidal Structure in Central Serous Chorioretinopathy.
Article in Investigative ophthalmology & visual science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Long-term follow-up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half-dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4.Acta ophthalmologica · 2026Trial
- Evaluation of anterior scleral thickness in pachychoroid pigment epitheliopathy, central serous chorioretinopathy and pachychoroid neovasculopathy.Japanese journal of ophthalmology · 2026Article
- Anterior Suprachoroidal Fluid Following Photodynamic Therapy for Chronic CSC: An Anterior-Segment Optical Coherence Tomography Study.Ophthalmology and therapy · 2026Article
- Comparison of the efficacy of subthreshold micropulse laser versus intravitreal anti-VEGF therapy for chronic central serous chorioretinopathy.Frontiers in medicine · 2026Article
- Three-Dimensional Choroidal Contour Mapping in Central Serous Chorioretinopathy and Fellow Eyes.Translational vision science & technology · 2025Article
- Choroidal circulation time by wide-field indocyanine green angiography in central serous chorioretinopathy.Japanese journal of ophthalmology · 2025Article
- Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy.Acta ophthalmologica · 2025Article
- Three-Dimensional Characteristics of Choroidal Vasculature Associated With Filling Delay in Central Serous Chorioretinopathy.Investigative ophthalmology & visual science · 2025Article
- Structural changes in vortex vein ampullae in eyes with pachychoroid-spectrum disorder.Scientific reports · 2025Article
- Choroidal arterial abnormality in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Relationship between Choroidal Thickness and Anterior Scleral Thickness in Patients with Keratoconus.Diagnostics (Basel, Switzerland) · 2024Article
- Central serous chorioretinopathy and the sclera: what we have learned so far.Japanese journal of ophthalmology · 2024Review
- Biomechanical properties measured with dynamic Scheimpflug analyzer in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Macular neovascularization and polypoidal choroidal vasculopathy: phenotypic variations, pathogenic mechanisms and implications in management.Eye (London, England) · 2024Review
- Vortex Veins in Eyes With Pachychoroid Spectrum Disorders Evaluated by the Adjusted Reverse 3-Dimensional Projection Model.Ophthalmology science · 2023Article
- Scleral changes in systemic lupus erythematosus patients using swept source optical coherence tomography.Frontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Central serous chorioretinopathy (CSC) is a retinal disorder characterized by serous retinal detachment with or without pigment epithelial detachment in the posterior pole of the eye. We aimed to elucidate the relationship between scleral thickness and choroidal structure in CSC eyes. Methods: This single-center retrospective study included 111 eyes of 111 CSC patients. Using swept-source optical coherence tomography, the horizontal cross-sectional images of the posterior choroid were converted to binary images by semiautomated software. The luminal and stromal areas of the choroid were measured, and the luminal/stromal (L/S) ratios of the whole choroid (WC), inner choroid, and outer choroid (OC) at 1500 µm, 3000 µm, and 7500 µm ranges centered on the fovea were calculated. Correlations of L/S ratio and age, spherical equivalent, axial length, subfoveal choroidal thickness (SCT), and scleral thickness were determined. Scleral thickness was measured vertically, 6 mm posterior to the scleral spur in four directions. Results: SCT and mean scleral thickness were significantly positively correlated with the L/S ratio in all ranges of WC and OC. Multiple regression analysis found that SCT and mean scleral thickness were significantly correlated with the L/S ratio, and the strength of correlation of mean scleral thickness (WC: 0.386, P < 0.001; OC: 0.391, P < 0.001) was greater than that of SCT (WC: 0.368, P < 0.001; OC: 0.383, P < 0.001) in 7500 µm range. Conclusions: Thick sclera appeared to play a role in an increase in the luminal component of the posterior choroid in CSC eyes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.