Evidence map›Paper›PMID 36662443›Full record

ArticleJournal of thrombosis and thrombolysis2023

Outcomes with use of extra-corporeal membrane oxygenation in high-risk pulmonary embolism: a national database perspective.

Mohamed Farhan Nasser, Ahmad Jabri, Shorabh Sharma, Laith Alhuneafat, Yazan Abu Omar, Vidya Krishnan, Scott J Cameron

Abstract read
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Article in Journal of thrombosis and thrombolysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed Farhan NasserHeart and Vascular Center, Case Western Reserve University, MetroHealth Campus, Cleveland, OH, USA.
Ahmad JabriHeart and Vascular Center, Case Western Reserve University, MetroHealth Campus, Cleveland, OH, USA.
Shorabh SharmaDepartment of Internal Medicine, St. Barnabas Hospital Health System, New York, NY, USA.
Laith AlhuneafatDepartment of Internal Medicine, Allegheny Health Network, Pittsburgh, PA, USA.
Yazan Abu OmarDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Vidya KrishnanDivision of Pulmonary, Critical Care and Sleep Medicine, Case Western Reserve University, MetroHealth Campus, Cleveland, OH, USA.
Scott J CameronSection of Vascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Foundation, Desk J-35, 9500 Euclid Ave, Cleveland, OH, 44195, USA. cameros3@ccf.org.ORCID http://orcid.org/0000-0002-9616-1540

Funding

Foundation for the National Institutes of Health HL158801-01
6 · The paper itself

Abstract

High-risk pulmonary embolism (PE) patients can be managed with systemic lysis, catheter-based therapies, or surgical embolectomy. Despite the advent of newer therapies, patients with high-risk PE remain with a 50-60% short-term mortality risk. In such patients, extracorporeal membrane oxygenation (ECMO) is increasingly utilized for hemodynamic support. To evaluate the outcomes of the use of ECMO in patients with high-risk PE. Using the National Inpatient Sample (NIS) database, we identified patients with high-risk PE using ICD 10 codes and compared in-hospital outcomes of patients with and without ECMO support. We identified 38,035 patients with high-risk PE, of whom 820 had undergone ECMO placement. Most patients who underwent ECMO were male (54%), white (65%), and with a mean age of 53.7 years. ECMO use was not associated with a meaningful difference in patient mortality when comparing treatment groups (OR, 1.32 ± 0.39; 0.74-2.35; p = 0.35). Rather, ECMO use was associated with a higher frequency of inpatient complications. ECMO use was not associated with a significant difference in patient mortality in patients with high-risk PE.

Indexed as

Extracorporeal Membrane OxygenationPulmonary EmbolismDatabases, FactualEmbolectomyFemaleHumansMaleMiddle AgedRetrospective StudiesThrombolytic TherapyCardiac arrest, bleedingExtra-corporeal membrane oxygenationHigh risk pulmonary embolismVenous thromboembolism

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.